Evidence map›Paper›PMID 34423298›Full record

ArticleBrain communications2021

Cerebrospinal fluid catecholamines in delirium and dementia.

Kristi Henjum, Kristin Godang, Else Quist-Paulsen, Ane-Victoria Idland, Bjørn Erik Neerland, Heidi Sandvig, Anniken Brugård, Johan Raeder, Frede Frihagen, Torgeir Bruun Wyller and 3 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The Locus Coeruleus Noradrenaline System in Delirium.Frontiers in aging neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kristi HenjumOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, 0424 Oslo, Norway.ORCID https://orcid.org/0000-0001-9147-7282
Kristin GodangSection of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, 0424 Oslo, Norway.
Else Quist-PaulsenDepartment Microbiology, Oslo University Hospital, 0424 Oslo, Norway.
Ane-Victoria IdlandOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, 0424 Oslo, Norway.
Bjørn Erik NeerlandOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, 0424 Oslo, Norway.
Heidi SandvigMedical Department, Kristiansund Hospital, Møre og Romsdal Hospital Trust, 6508 Kristiansund, Norway.
Anniken BrugårdOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, 0424 Oslo, Norway.
Johan RaederDepartment of Anesthesiology, Oslo University Hospital, 0424 Oslo, Norway.
Frede FrihagenDivision of Orthopedic Surgery, Oslo University Hospital, 0424 Oslo, Norway.
Torgeir Bruun WyllerOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, 0424 Oslo, Norway.
Bjørnar HasselDepartment of Neurohabilitation, Oslo University Hospital, 0424 Oslo, Norway.
Jens BollerslevDepartment of Geriatric Medicine, Institute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway.
Leiv Otto WatneOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, 0424 Oslo, Norway.
Oslo University Hospital · NOKristiansund Sykehus · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine and noradrenaline are functionally connected to delirium and have been targets for pharmacological interventions but the biochemical evidence to support this notion is limited. To study the CSF levels of dopamine, noradrenaline and the third catecholamine adrenaline in delirium and dementia, these were quantified in three patient cohorts: (i) cognitively normal elderly patients (

Indexed as

catecholamineCSF biomarkersdeliriumdementiahip fracture

Identifiers

PMID34423298
PMCPMC8374970
OpenAlexW3174183795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.