Evidence map›Paper›PMID 34423272›Full record

ArticleACS pharmacology & translational science2021

Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site.

Anne-Sophie Depuydt, Jérôme Rihon, Olivier Cheneval, Michiel Vanmeert, Christina I Schroeder, David J Craik, Eveline Lescrinier, Steve Peigneur, Jan Tytgat

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS pharmacology & translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. T-Type Calcium Channels: A Mixed Blessing.International journal of molecular sciences · 2022
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Anne-Sophie DepuydtToxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg, Leuven 3000, Belgium.
Jérôme RihonLaboratory of Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Leuven 3000, Belgium.
Olivier ChenevalInstitute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, 4072 Queensland Australia.
Michiel VanmeertLaboratory of Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Leuven 3000, Belgium.
Christina I SchroederInstitute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, 4072 Queensland Australia.ORCID https://orcid.org/0000-0002-6737-6374
David J CraikInstitute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, 4072 Queensland Australia.ORCID https://orcid.org/0000-0003-0007-6796
Eveline LescrinierLaboratory of Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0001-7066-4329
Steve PeigneurToxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0003-0504-5702
Jan TytgatToxicology and Pharmacology, University of Leuven (KU Leuven), Campus Gasthuisberg, Leuven 3000, Belgium.
KU Leuven · BERega Institute for Medical Research · BEAustralian Research Council · AUNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-type calcium (Ca

Identifiers

PMID34423272
PMCPMC8369677
OpenAlexW3167684579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.