Evidence map›Paper›PMID 34423148›Full record

ArticleHeliyon2021

Comparing radiological presentations of first and second strains of COVID-19 infections in a low-resource country.

Edmund K K Brakohiapa, Benjamin D Sarkodie, Benard O Botwe, Klenam Dzefi-Tettey, Dorothea A Anim, Emmanuel K M Edzie, Philip N Goleku, Bashiru B Jimah, Adu Tutu Amankwa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Edmund K K BrakohiapaDepartment of Radiology, University of Ghana Medical School, Ghana.
Benjamin D SarkodieDepartment of Radiology, University of Ghana Medical School, Ghana.
Benard O BotweDepartment of Radiography, School of Biomedical & Allied Health Sciences, College of Health Sciences, University of Ghana, P. O Box KB143, Korle Bu Campus, Accra, Ghana.
Klenam Dzefi-TetteyDepartment of Radiology, Korle-Bu Teaching Hospital, Ghana.
Dorothea A AnimDepartment of Radiology, Korle-Bu Teaching Hospital, Ghana.
Emmanuel K M EdzieDepartment of Medical Imaging, College of Health and Allied Sciences, University of Cape Coast, Ghana.
Philip N GolekuDepartment of Medical Imaging, College of Health and Allied Sciences, University of Cape Coast, Ghana.
Bashiru B JimahDepartment of Medical Imaging, College of Health and Allied Sciences, University of Cape Coast, Ghana.
Adu Tutu AmankwaDepartment of Radiology, Komfo Anokye Teaching Hospital, Kumasi University of Science and Technology, Ghana.
University of Cape Coast · GHUniversity of Ghana · GHKorle Bu Teaching Hospital · GHKomfo Anokye Teaching Hospital · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe novel corona virus popularly referred to as COVID-19 disease and SARS-CoV-2 was first detected in Wuhan, China in December 2019. It was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. In Ghana, the first two cases of COVID-19 infection were recorded on March 13, 2020 with a strain imported from Europe. In December 2020, a new strain from South Africa was detected in Ghana which was associated with higher transmission rates, severity of the disease, and higher number of recorded deaths. Our study aimed to record notable differences and similarities between infections due to the initial, and second strains of COVID-19 infections detected in Ghana during the last 12-months.

methodThis was a retrospective study involving 50 patients infected with the first strain, and another 50 patients infected with the second strain of the SARS-CoV-2 virus. Microsoft Excel-2013 was the analytical tool.

resultsThe data analysis supported publications suggesting that the new strain of the virus caused more severe infections, which were manifested on high resolution CT (HRCT) scans as more widespread alveolar disease, most commonly presenting as large areas of consolidation.

conclusionDespite numerous similarities in terms of the manifestation of COVID-19 infection on HRCT scans, notable difference supporting the notion of increased virulence and severity of disease were also recorded. The study findings demonstrate the need for heightened and sustained preventive measures needed to reduce, and eventually curb COVID-19 infection and mortality rates associated with the introduction of new virulent strains.

Indexed as

COVID-19Lung diseasesMultidetector computed tomographySARS-CoV-2

Identifiers

PMID34423148
PMCPMC8372493
OpenAlexW3196206072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.