Evidence map›Paper›PMID 34423073›Full record

ArticleJournal of alcoholism and drug dependence2021

Executive Function and Contingency Management in Methamphetamine Use Disorder.

Lara J van Nunen, Marilyn T Lake, Jonathan C Ipser, Dan J Stein, Steven J Shoptaw, Edythe D London

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of alcoholism and drug dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. The Association between Childhood Trauma on Executive Functioning and Treatment Outcomes among Individuals with Methamphetamine Use Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lara J van NunenDepartment of Psychiatry and Mental Health, University of Cape Town, Neuroscience Institute, South Africa.
Marilyn T LakeDepartment of Psychiatry and Mental Health, University of Cape Town, Neuroscience Institute, South Africa.
Jonathan C IpserDepartment of Psychiatry and Mental Health, University of Cape Town, Neuroscience Institute, South Africa.
Dan J SteinSouth African Medical Research Council Unit on Risk & Resilience in Mental Disorders.
Steven J ShoptawDepartment of Psychiatry and Mental Health, University of Cape Town, Neuroscience Institute, South Africa.
Edythe D LondonDepartment of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, Los Angeles, California, United States of America.
University of California, Los Angeles · US

Funding

Combating craving with contingency management: neuroplasticity and methamphetamine abuse in South AfricaR21DA040492 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHOPTAW, STEVEN J · 2015 to 2017
$311k
NIDA NIH HHS R21 DA040492
6 · The paper itself

Abstract

objectivesContingency management is a promising intervention for Methamphetamine Use Disorder (MUD).Impaired executive function may decrease adherence to such treatment, but there are few data on whether impairment in executive function predicts treatment outcomes. We therefore evaluated whether baseline performance on tests of executive function predicted treatment response in a trial of contingency management for MUD.

methodsThirty participants with MUD and 23 healthy controls performed the Connors Continuous Performance Task (CPT) and the Trail Making Task. MUD participants then entered an 8-week contingency management trial. Participants were categorized as responders (n=17; no methamphetamine-positive urine tests) or non-responders (n=13; >1 positive test). The Kruskal-Wallis test was used to compare scores in participants with MUD and healthy controls, and in responders versus non-responders.

resultsParticipants withMUD performed worse than controls on the CPT (d-prime) (p=0.012); non-responders performed worse than responders (p = 0.034). Performance of MUD participants did not differ significantly from controls on the Trail Making Task B (time to completion), but variation was high with non-responders performing worse than responders (p=0.013).

conclusionThese findings suggest that tests of executive function at baseline may be useful in predicting treatment response in MUD. Future work in larger samples may ultimately allow a more personalized treatment approach to methamphetamine use disorder.

Indexed as

Contingency managementExecutive functionMethamphetamine use disorder

Identifiers

PMID34423073
PMCPMC8378238
OpenAlexW3163407909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.