Evidence map›Paper›PMID 34423046›Full record

Observational studyJournal of diabetes research2021

Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema.

Eleni Dimitriou, Theodoros N Sergentanis, Vaia Lambadiari, George Theodossiadis, Panagiotis Theodossiadis, Irini Chatziralli

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eleni Dimitriou *2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.
Theodoros N Sergentanis *Department of Clinical Therapeutics, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Vaia Lambadiari2nd Department of Internal Medicine, Research Institute and Diabetes Center, National and Kapodistrian University of Athens, Athens, Greece.
George Theodossiadis2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.
Panagiotis Theodossiadis2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.
Irini Chatziralli2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0001-8523-1024
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the potential association between peripheral blood biomarkers and morphological characteristics of retinal imaging in patients with diabetic macular edema (DME).

methodsParticipants in this cross-sectional study were 36 consecutive patients (36 eyes) with treatment-naïve DME, who underwent spectral domain-optical coherence tomography (SD-OCT), fundus photography, and fundus fluorescein angiography (FFA). In addition, peripheral blood samples were taken to evaluate full blood count and biochemical parameters. Correlation between imaging characteristics and laboratory parameters was examined.

resultsEyes with central subfield thickness greater than 405

conclusionSpecific imaging morphological characteristics were found to be associated with laboratory parameters in patients with DME. These findings may shed light on the pathophysiology of DME and its correlation with the development of specific clinical signs.

Indexed as

Fluorescein AngiographyPhotographyTomography, Optical CoherenceAgedBiomarkersCross-Sectional StudiesDiabetes Mellitus, Type 2Diabetic RetinopathyFemaleHumansMacular EdemaMaleMiddle AgedPredictive Value of TestsRetinaBiomarkers

Identifiers

PMID34423046
PMCPMC8378977
OpenAlexW3195657134

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.