Evidence map›Paper›PMID 34422964›Full record

ArticleAnnals of translational medicine2021

Incidence and predictors of 30-day hospital readmissions for liver cirrhosis: insights from the United States National Readmissions Database.

Sushil Kumar Garg, Hemant Goyal, Itegbemie Obaitan, Pir Ahmad Shah, Shashank Sarvepalli, Loretta Lynn Jophlin, Dupinder Singh, Sumeet Asrani, Patrick S Kamath, Michael D Leise

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  4. Clinical decision instruments for predicting mortality in patients with cirrhosis seeking emergency department care.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Sushil Kumar GargDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Hemant GoyalMercer University School of Medicine, Macon, GA, USA.
Itegbemie ObaitanDepartment of Gastroenterology and Hepatology, University of Minnesota, Minneapolis, MN, USA.
Pir Ahmad ShahBeth Israel Deaconess Medical Center, Boston, MA, USA.
Shashank SarvepalliDepartment of Hospital Medicine, Cleveland Clinic, Cleveland, OH, USA.
Loretta Lynn JophlinDivision of Gastroenterology-Hepatology, University of Nebraska Medical Center, Omaha, NE, USA.
Dupinder SinghDepartment of Gastroenterology and Hepatology, University of Minnesota, Minneapolis, MN, USA.
Sumeet AsraniBaylor University Medical Center, Baylor Scott and White, Dallas, TX, USA.
Patrick S KamathDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Michael D LeiseDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USUniversity of Minnesota · USBaylor University Medical Center · USBeth Israel Deaconess Medical Center · USCleveland Clinic · USMercer University · USUniversity of Nebraska Medical Center · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
Research Training in GastroenterologyT32DK083266 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Hashem B El-Serag, FASIHA KANWAL · 2010 to 2026
$2.3M
NIDDK NIH HHS P30 DK056338NIDDK NIH HHS T32 DK083266
6 · The paper itself

Abstract

backgroundCirrhosis is associated with substantial inpatient morbidity and mortality. This study aimed to determine the trends in 30-day hospital readmission rates among patients with cirrhosis and identify factors associated with these readmissions.

methodsWe conducted a retrospective analysis of data retrieved from the Nationwide Readmissions Database to determine trends in 30-day readmission for patients discharged with a diagnosis of cirrhosis in 2010 through 2014. Multivariate logistic regression analysis was used to identify predictors of readmission.

resultsAmong 303,346 patients identified from the database, the 30-day readmission rate for patients with a discharge diagnosis of cirrhosis was 31.4% (n=95,298). The trends in the readmission rates remained steady during the study period. On multivariate analysis, female sex, age 45 years or older, esophagogastroduodenoscopy (EGD) during admission, and disposition to a short-term care facility or skilled nursing facility protected against readmissions. In contrast, coverage by Medicaid insurance, admission during a weekend, nonalcoholic cause of cirrhosis, and history of hepatic encephalopathy and ascites were associated with readmission.

conclusionsWe found an exceptionally high 30-day readmission rate in patients with cirrhosis, although it remained stable during the study period. This study identified some modifiable factors such as disposition to a short-term care facility or skilled nursing facility and patients' attendance of alcohol rehabilitation facilities that could decrease the likelihood of readmission and could inform local and national healthcare policymakers.

Indexed as

30-day readmissionCirrhosishealthcare costnational readmission database

Identifiers

PMID34422964
PMCPMC8339830
OpenAlexW3178624286

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.