Evidence map›Paper›PMID 34422898›Full record

ArticleFrontiers in molecular biosciences2021

Structural and Genomic Insights Into Pyrazinamide Resistance in

Tanushree Tunstall, Jody Phelan, Charlotte Eccleston, Taane G Clark, Nicholas Furnham

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. A simplified pyrazinamidase test forJournal of clinical microbiology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tanushree TunstallDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Jody PhelanDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Charlotte EcclestonDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Taane G ClarkDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Nicholas FurnhamDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
London School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MR/M01360X/1Medical Research Council MR/N010469/1Medical Research Council MR/R020973/1Medical Research Council MR/R025576/1Medical Research Council MR/T000171/1
6 · The paper itself

Abstract

Resistance to drugs used to treat tuberculosis disease (TB) continues to remain a public health burden, with missense point mutations in the underlying

Indexed as

biophysical effectsFoldXmCSMMycobacterium tuberculosisnon-synonymous Single Nucleotide PolymorphismsnsSNPspncAthermodynamic stability

Identifiers

PMID34422898
PMCPMC8372558
OpenAlexW3184371182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.