Evidence map›Paper›PMID 34422882›Full record

ReviewFrontiers in nutrition2021

Gut Microbiota and Their Role in Health and Metabolic Disease of Dairy Cow.

Qingbiao Xu, Qinqin Qiao, Ya Gao, Jinxiu Hou, Mingyang Hu, Yufeng Du, Ke Zhao, Xiang Li

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
24.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 147 citations in OpenAlex.

  1. Trial
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  7. Effects of inactivatedAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Article
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  11. Review
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  20. Animals : an open access journal from MDPI · 2025
    Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Qingbiao XuCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Qinqin QiaoCollege of Information Engineering, Fuyang Normal University, Fuyang, China.
Ya GaoCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Jinxiu HouCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Mingyang HuCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Yufeng DuCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Ke ZhaoInstitute of Food Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Xiang LiCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CNFuyang Normal University · CNZheJiang Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ruminants are mostly herbivorous animals that employ rumen fermentation for the digestion of feed materials, including dairy cows. Ruminants consume plant fibre as their regular diet, but lack the machinery for their digestion. For this reason, ruminants maintain a symbiotic relation with microorganisms that are capable of producing enzymes to degrade plant polymers. Various species of microflora including bacteria, protozoa, fungi, archaea, and bacteriophages are hosted at distinct concentrations for accomplishing complete digestion. The ingested feed is digested at a defined stratum. The polysaccharic plant fibrils are degraded by cellulolytic bacteria, and the substrate formed is acted upon by other bacteria. This sequential degradative mechanism forms the base of complete digestion as well as harvesting energy from the ingested feed. The composition of microbiota readily gets tuned to the changes in the feed habits of the dairy cow. The overall energy production as well as digestion is decided by the intactness of the resident communal flora. Disturbances in the homogeneity gastrointestinal microflora has severe effects on the digestive system and various other organs. This disharmony in communal relationship also causes various metabolic disorders. The dominance of methanogens sometimes lead to bloating, and high sugar feed culminates in ruminal acidosis. Likewise, disruptive microfloral constitution also ignites reticuloperitonitis, ulcers, diarrhoea, etc. The role of symbiotic microflora in the occurrence and progress of a few important metabolic diseases are discussed in this review. Future studies in multiomics provides platform to determine the physiological and phenotypical upgradation of dairy cow for milk production.

Indexed as

dairy cowgastrointestinal microflorametabolic diseasesomicsrumenruminants

Identifiers

PMID34422882
PMCPMC8371392
OpenAlexW3196158471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.