ArticleFrontiers in cell and developmental biology2021
PI3K Plays an Essential Role in Planarian Regeneration and Tissue Maintenance.
Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 citing papers in PubMed, 9 citations in OpenAlex.
- RNA mJournal of advanced research · 2026Article
- Unraveling the role ofZoological research · 2026Article
- Mining differentially expressed genes during paratomy in the transcriptome of the flatworm Stenostomum leucops.Scientific reports · 2024Article
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9 authors at 2 institutions in 1 country.
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Abstract
Phosphatidylinositol 3-kinase (PI3K) signaling plays a central role in various biological processes, and its abnormality leads to a broad spectrum of human diseases, such as cancer, fibrosis, and immunological disorders. However, the mechanisms by which PI3K signaling regulates the behavior of stem cells during regeneration are poorly understood. Planarian flatworms possess abundant adult stem cells (called neoblasts) allowing them to develop remarkable regenerative capabilities, thus the animals represent an ideal model for studying stem cells and regenerative medicine
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