Evidence map›Paper›PMID 34422787›Full record

ArticleFrontiers in physics2021

Regulation of Actin Bundle Mechanics and Structure by Intracellular Environmental Factors.

Nicholas Castaneda, Jinho Park, Ellen Hyeran Kang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The structure and mechanics of the cell cortex depend on the location and adhesion state.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Silactins and Structural Diversity of Biosilica in Sponges.Biomimetics (Basel, Switzerland) · 2024
    Article
  6. CdSe/ZnS Quantum Dots' Impact on In Vitro Actin Dynamics.International journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Actin dynamics in protein homeostasis.Bioscience reports · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nicholas Castaneda *NanoScience Technology Center, University of Central Florida, Orlando, FL, United States.
Jinho Park *NanoScience Technology Center, University of Central Florida, Orlando, FL, United States.
Ellen Hyeran KangNanoScience Technology Center, University of Central Florida, Orlando, FL, United States.
University of Central Florida · US

Funding

Molecular Analysis of the Chlamydia trachomatis virulence factor TarpR01AI139242 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI JEWETT, TRAVIS JAMES · 2019 to 2022
$2.3M
NIAID NIH HHS R01 AI139242
6 · The paper itself

Abstract

The mechanical and structural properties of actin cytoskeleton drive various cellular processes, including structural support of the plasma membrane and cellular motility. Actin monomers assemble into double-stranded helical filaments as well as higher-ordered structures such as bundles and networks. Cells incorporate macromolecular crowding, cation interactions, and actin-crosslinking proteins to regulate the organization of actin bundles. Although the roles of each of these factors in actin bundling have been well-known individually, how combined factors contribute to actin bundle assembly, organization, and mechanics is not fully understood. Here, we describe recent studies that have investigated the mechanisms of how intracellular environmental factors influence actin bundling. This review highlights the effects of macromolecular crowding, cation interactions, and actin-crosslinking proteins on actin bundle organization, structure, and mechanics. Understanding these mechanisms is important in determining

Indexed as

actin bundlesactin crosslinkerbending stiffnesscation interactionsmacromolecular crowding

Identifiers

PMID34422787
PMCPMC8376200
OpenAlexW3170263439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.