Evidence map›Paper›PMID 34422675›Full record

ArticleFrontiers in cellular and infection microbiology2021

Protozoan-Viral-Bacterial Co-Infections Alter Galectin Levels and Associated Immunity Mediators in the Female Genital Tract.

Raina N Fichorova, Allison K DeLong, Susan Cu-Uvin, Caroline C King, Denise J Jamieson, Robert S Klein, Jack D Sobel, David Vlahov, Hidemi S Yamamoto, Kenneth H Mayer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Progress in interventions for vaginal microecology.Frontiers in cellular and infection microbiology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Infection and immunity · 2023
    Review
  6. Article
  7. Review
  8. The L-Rhamnose Biosynthetic Pathway inInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Review
  11. Microbiome research reports · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Raina N FichorovaDepartment of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.
Allison K DeLongCenter for Statistical Sciences, School of Public Health, Brown University, Providence, RI, United States.
Susan Cu-UvinDepartment of Obstetrics and Gynecology, Brown University, The Miriam Hospital, Providence, RI, United States.
Caroline C KingNational Center for Chronic Disease Prevention and Health Promotion/Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Denise J JamiesonDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, United States.
Robert S KleinHudson Infectious Diseases Associates, Briarcliff Manor, NY, United States.
Jack D SobelDivision of Infectious Diseases, School of Medicine, Wayne State University, Detroit, MI, United States.
David VlahovDepartment of Community Health Systems, School of Nursing, University of California at San Francisco, San Francisco, CA, United States.
Hidemi S YamamotoDepartment of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States.
Kenneth H MayerThe Fenway Institute, Fenway Health, Boston, MA, United States.
Harvard University · USBeth Israel Deaconess Hospital · USBrown University · USCenters for Disease Control and Prevention · USEmory University · USMiriam Hospital · USUnity Health System · USWayne State University · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Molecular T. vaginalis-host interactions in relevance to inflammatory sequelaeR01AI079085 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI FICHOROVA, RAINA N. · 2009 to 2012
$3.0M
T. vaginalis viruses as mucosal immunity modifiers with impact on women's healthR56AI091889 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI FICHOROVA, RAINA N. · 2012 to 2012
$877k
T. vaginalis viruses as mucosal immunity modifiers with impact on women's healthRC1AI086788 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI FICHOROVA, RAINA N. · 2010 to 2010
$499k
NIAID NIH HHS P30 AI042853NIAID NIH HHS R01 AI079085NIAID NIH HHS R56 AI091889NIAID NIH HHS RC1 AI086788
6 · The paper itself

Abstract

Co-infections with sexually transmittable pathogens are common and more likely in women with disturbed vaginal bacteriome. Among those pathogens, the protozoan parasite

Indexed as

CoinfectionTrichomonas VaginitisVirus DiseasesBacteriaFemaleGalectin 3HumansPrevotellaGalectin 3bacterial vaginosisendosymbiont virusesgalectin-1galectin-3galectin-9HPVPrevotella biviaTrichomonas vaginalis

Identifiers

PMID34422675
PMCPMC8375472
OpenAlexW3192535478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.