Evidence map›Paper›PMID 34422654›Full record

ArticleFrontiers in oncology2021

Genetic Polymorphisms in CD35 Gene Contribute to the Susceptibility and Prognosis of Hepatocellular Carcinoma.

Limei Luo, Qin Li, Zhenzhen Su, Lixin Li, Bei Cai, Yufu Peng, Yangjuan Bai, Fei Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Complement system in cancer: friend or foe of immunotherapy.Journal for immunotherapy of cancer · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Limei LuoDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Qin LiDepartment of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, China.
Zhenzhen SuDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Lixin LiDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Bei CaiDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Yufu PengDepartment of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, China.
Yangjuan BaiDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Fei LiuDepartment of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD35, an important molecule implicated in inflammation and immunity, is reportedly associated with several cancers. However, very few studies have investigated the relationship between

Indexed as

CD35genetic variationhepatocellular carcinomaprognosissusceptibility

Identifiers

PMID34422654
PMCPMC8374953
OpenAlexW3128088281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.