Evidence map›Paper›PMID 34422643›Full record

ArticleFrontiers in oncology2021

Robust Prognostic Subtyping of Muscle-Invasive Bladder Cancer Revealed by Deep Learning-Based Multi-Omics Data Integration.

Xiaolong Zhang, Jiayin Wang, Jiabin Lu, Lili Su, Changxi Wang, Yuhua Huang, Xuanping Zhang, Xiaoyan Zhu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xiaolong ZhangSchool of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Jiayin WangSchool of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Jiabin LuDepartment of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.
Lili SuSchool of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Changxi WangSchool of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Yuhua HuangSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Xuanping ZhangSchool of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Xiaoyan ZhuSchool of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Xi'an Jiaotong University · CNSun Yat-sen University · CNSun Yat-sen University Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle-invasive bladder cancer (MIBC) is the most common urinary system carcinoma associated with poor outcomes. It is necessary to develop a robust classification system for prognostic prediction of MIBC. Recently, increasing omics data at different levels of MIBC were produced, but few integration methods were used to classify MIBC that reflects the patient's prognosis. In this study, we constructed an autoencoder based deep learning framework to integrate multi-omics data of MIBC and clustered samples into two different subgroups with significant overall survival difference (

Indexed as

deep learningmulti-omicsmuscle-invasive bladder cancerprognosissubtyping

Identifiers

PMID34422643
PMCPMC8378227
OpenAlexW3192984034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.