ArticleJournal of thoracic disease2021
Post-implantation syndrome after frozen elephant trunk is associated with the volume of new-onset aortic thrombus.
Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection.Journal of vascular surgery cases and innovative techniques · 2025Article
- Aortic endograft infection after thoracic endovascular aortic repair: two case reports and literature review.Frontiers in cardiovascular medicine · 2025Article
- The frozen elephant trunk technique in acute aortic dissection: the ultimate solution? An institutional experience.Frontiers in cardiovascular medicine · 2024Article
- Unveiling the Enigma of Post-implantation Syndrome Following Aortic Dissection Repair: A Case Report.Cureus · 2023Article
- Impact of Frozen and Conventional Elephant Trunk on Aortic New-Onset Thrombus and Inflammatory Response.Diagnostics (Basel, Switzerland) · 2022Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-implantation syndrome (PIS) is defined as non-infectious continuous fever and a concomitant rise in inflammatory markers shortly after endovascular aortic repair. PIS occurrence after hybrid procedures, such as the frozen elephant trunk (FET) technique, has not been adequately investigated. The current study aims to define the incidence of PIS after the FET and to identify possible risk factors associated with its occurrence.
methodsThe clinical charts of 59 patients undergoing the FET between February 2015 and April 2020 were reviewed retrospectively. The occurrence of PIS was defined as the presence of fever (>38 °C lasting longer than one day during the hospitalisation) and leucocytosis (white blood cell count >12,000/µL). Patients with concomitant conditions possibly leading to fever and/or leucocytosis were excluded. Beside demographic and procedure-related data, serum/plasma inflammatory markers were evaluated before surgery and daily up to seven days postoperatively. Computed tomography scans (CT) were examined to calculate the volume of pre-existent and new-onset mural thrombus after the FET.
resultsThirty-eight patients met the inclusion criteria. The study cohort was divided into two groups based on the occurrence of PIS (17 cases; 44.7%). Patients with PIS were significantly younger than those without PIS (53.5±8.9
conclusionsPIS can occur after the frozen elephant trunk procedure. The volume of new-onset thrombus seems to be associated with an increased incidence of PIS. These findings need to be confirmed in larger patient cohorts.
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