Evidence map›Paper›PMID 34422343›Full record

ArticleJournal of thoracic disease2021

Tracheostomy for COVID-19 respiratory failure: timing, ventilatory characteristics, and outcomes.

Janice L Farlow, Pauline K Park, Michael W Sjoding, Stephen G Kay, Ross Blank, Kelly M Malloy, Laraine Washer, Lena M Napolitano, Venkatakrishna Rajajee, Michael J Brenner and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Early versus late tracheostomy in critically ill COVID-19 patients.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Article
  3. Article
  4. Development of the Tracheostomy Well-Being Score in critically ill patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Observational
  5. Article
  6. Article
  7. The surgical airway in the COVID-19 era.Operative techniques in otolaryngology--head and neck surgery · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Janice L FarlowDepartment of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Pauline K ParkDepartment of Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Michael W SjodingDivision of Pulmonary and Critical Care, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Stephen G KayDivision of Pulmonary and Critical Care, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Ross BlankDepartment of Anesthesia, Michigan Medicine, Ann Arbor, MI, USA.
Kelly M MalloyDepartment of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Laraine WasherDivision of Infectious Diseases, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, USA.
Lena M NapolitanoDepartment of Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Venkatakrishna RajajeeDepartment of Neurosurgery, Michigan Medicine, Ann Arbor, MI, USA.
Michael J BrennerDepartment of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Steven B ChinnDepartment of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Jose De CardenasDepartment of Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Michigan Medicine · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Integrated Analysis of Germline and Somatic Mutations in Young, Low-Risk and Older, High-Risk Oral Cavity CancerK08CA226350 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHINN, STEVEN BENNETT · 2018 to 2021
$882k
Data-Driven Identification of the Acute Respiratory Distress SyndromeK01HL136687 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SJODING, MICHAEL WILLIAM · 2017 to 2021
$862k
NCATS NIH HHS UL1 TR002240NCI NIH HHS K08 CA226350NHLBI NIH HHS K01 HL136687
6 · The paper itself

Abstract

backgroundWhereas data from the pre-pandemic era have demonstrated that tracheostomy can accelerate liberation from the ventilator, reduce need for sedation, and facilitate rehabilitation, concerns for healthcare worker safety have led to disagreement on tracheostomy placement in COVID-19 patients. Data on COVID-19 patients undergoing tracheostomy may inform best practices. Thus, we report a retrospective institutional cohort experience with tracheostomy in ventilated patients with COVID-19, examining associations between time to tracheostomy and duration of mechanical ventilation in relation to patient characteristics, clinical course, and survival.

methodsClinical data were extracted for all COVID-19 tracheostomies performed at a quaternary referral center from April-July 2020. Outcomes studied included mortality, adverse events, duration of mechanical ventilation, and time to decannulation.

resultsAmong 64 COVID-19 tracheostomies (13% of COVID-19 hospitalizations), patients were 64% male and 42% African American, with a median age of 54 (range, 20-89). Median time to tracheostomy was 22 (range, 7-60) days and median duration of mechanical ventilation was 39.4 (range, 20-113) days. Earlier tracheostomy was associated with shortened mechanical ventilation (R

conclusionsTracheostomy was associated with swifter liberation from the ventilator and acceptable safety for physicians in this series of critically ill COVID-19 patients. Patient mortality was not increased relative to historical data on acute respiratory distress syndrome (ARDS). Future studies are required to establish conclusions of causality regarding tracheostomy timing with mechanical ventilation, complications, or mortality in COVID-19 patients.

Indexed as

coronavirus 2COVID-19mechanical ventilationsevere acute respiratory syndromeTracheostomy

Identifiers

PMID34422343
PMCPMC8339767
OpenAlexW3180446202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.