Evidence map›Paper›PMID 34422201›Full record

ArticleThe Pan African medical journal2021

Human papillomavirus-related multiphenotypic sinonasal carcinoma: a clinico-pathological dilemma case report.

Nouha Ben Abdeljelil, Samiha Mabrouk, Souheil Khalfaoui, Mahdi Farjaoui, Ahlem Bellalah, Abdefattah Zakhama, Rim Hadhri

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nouha Ben AbdeljelilDepartment of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Samiha MabroukDepartment of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Souheil KhalfaouiDepartment of Neurosurgery, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Mahdi FarjaouiDepartment of Otorhinolaryngology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Ahlem BellalahDepartment of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Abdefattah ZakhamaDepartment of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Rim HadhriDepartment of Pathology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Hospital Fatuma Bourguiba Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC), is a new entity that is restricted to the sinonasal tract and is associated with high-risk HPV. This tumor is suggested to have an indolent behavior with a better prognosis than other carcinomas. We report a unique case of HMSC with a locally aggressive behavior. It is about a 61-year-old men presented with 12 months of unilateral progressive olfactory dysfunction accompanied by exophthalmia of the left eye, declining vision and headaches for 6 months. Computed tomography imaging revealed a voluminous mass occupying the ethmoid, maxillary and frontal sinus with bony destruction of the left ethmoidal blade. Histology showed a tumor composed of variably sized nests, separated by thick mucoid stroma. Tumor cells are plasmacytoid with hyperchromatic nuclei and frequent mitoses. Immunohistochemistry revealed that these cells were positive for cytokeratin AE1/AE3, p16 and negative for CK7, CK20, CD117, p40, p63, S100, synaptophysin and chromogranin.

Indexed as

Disease ProgressionHumansImmunohistochemistryMaleMiddle AgedPapillomavirus InfectionsParanasal Sinus NeoplasmsTomography, X-Ray Computedcarcinomacase reportHuman papillomavirusimmunohistochemistrysinonasal tract

Identifiers

PMID34422201
PMCPMC8363977
OpenAlexW3171639924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.