Evidence map›Paper›PMID 34422088›Full record

ArticleComputational and mathematical methods in medicine2021

Radiomics Analysis Based on Automatic Image Segmentation of DCE-MRI for Predicting Triple-Negative and Nontriple-Negative Breast Cancer.

Mingming Ma, Liangyu Gan, Yuan Jiang, Naishan Qin, Changxin Li, Yaofeng Zhang, Xiaoying Wang

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mingming MaDepartment of Radiology, Peking University First Hospital, Beijing, China.
Liangyu GanBreast Disease Center, Peking University First Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-5313-2571
Yuan JiangBeijing Smart Tree Medical Technology co. Ltd., Beijing, China.
Naishan QinBeijing Smart Tree Medical Technology co. Ltd., Beijing, China.
Changxin LiBeijing Smart Tree Medical Technology co. Ltd., Beijing, China.
Yaofeng ZhangBeijing Smart Tree Medical Technology co. Ltd., Beijing, China.
Xiaoying WangDepartment of Radiology, Peking University First Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-9822-961X
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether quantitative radiomics features extracted from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) could be used to differentiate triple-negative breast cancer (TNBC) and nontriple-negative breast cancer (non-TNBC). MATERIALS AND

methodsThis retrospective study included DCE-MRI images of 81 breast cancer patients (44 TNBC and 37 non-TNBC) from August 2018 to October 2019. The MR scans were achieved at a 1.5 T MR scanner. For each patient, the largest tumor mass was selected to analyze. Three-dimensional (3D) images of the regions of interest (ROIs) were automatically segmented on the third DCE phase by a deep learning segmentation model; then, the ROIs were checked and revised by 2 radiologists. DCE-MRI radiomics features were extracted from the 3D tumor volume. The patients were randomly divided into training (

resultsThe radiomics model based on 15 features got the best performance. The AUC achieved 0.741 for the cross-validation, and 0.867 for the independent testing cohort.

conclusionThe radiomics model based on automatic image segmentation of DCE-MRI can be used to distinguish TNBC and non-TNBC.

Indexed as

Deep LearningAdultAgedBreast NeoplasmsChinaCohort StudiesComputational BiologyContrast MediaFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMiddle AgedPrincipal Component AnalysisRetrospective StudiesROC CurveContrast Media

Identifiers

PMID34422088
PMCPMC8371618
OpenAlexW3188942978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.