Evidence map›Paper›PMID 34421906›Full record

ArticleFrontiers in immunology2021

MiR-130a-3p Alleviates Liver Fibrosis by Suppressing HSCs Activation and Skewing Macrophage to Ly6C

Lei Liu, Peng Wang, Yun-Sheng Wang, Ya-Nan Zhang, Chen Li, Zi-Yin Yang, Zi-Hao Liu, Ting-Zheng Zhan, Jing Xu, Chao-Ming Xia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Inhibiting Liver Autophagy and Promoting Hepatocyte Apoptosis byTropical medicine and infectious disease · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lei LiuDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Peng WangCenter for Genetic Epidemiology and Genomics, School of Public Health, Medical College of Soochow University, Suzhou, China.
Yun-Sheng WangDepartment of Endocrinology, Second People's Hospital of Hefei, Anhui, China.
Ya-Nan ZhangDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Chen LiDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Zi-Yin YangDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Zi-Hao LiuDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Ting-Zheng ZhanDepartment of Parasitology, Guangxi Medical University, Nanning, China.
Jing XuDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Chao-Ming XiaDepartment of Parasitology, Medical College of Soochow University, Suzhou, China.
Soochow University · CNGuangxi Medical University · CNThird People's Hospital of Hefei · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidences have highlighted the crucial role of microRNAs (miRNAs) in the liver cirrhosis, but the relationship between miR-130a-3p and liver cirrhosis is not entirely clear. As we all know, schistosomiasis, as one of the zoonoses, can lead to liver cirrhosis when it advances. In this study, we investigated the biological functions of miR-130a-3p on the liver fibrosis of schistosomiasis

Indexed as

AnimalsAntigens, LyApoptosisCase-Control StudiesCell LineCell ProliferationCollagen Type IDisease Models, AnimalFemaleHepatic Stellate CellsHost-Parasite InteractionsHumansLiverLiver CirrhosisMacrophagesMiceAntigens, LyCollagen Type ILy-6C antigen, mouseMicroRNAsMIRN130 microRNA, humanMIRN130 microRNA, mouseHSCsliver fibrosisLy6ClomiR-130a-3pschistosomiasis

Identifiers

PMID34421906
PMCPMC8375151
OpenAlexW3189996755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.