SynthesisFrontiers in psychiatry2021
The Effectiveness of Eye Movement Desensitization and Reprocessing Toward Adults With Major Depressive Disorder: A Meta-Analysis of Randomized Controlled Trials.
Synthesis in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- EMDR as Treatment Option for Conditions Other Than PTSD: A Systematic Review.Frontiers in psychology · 2021Pooled it
- Effects of virtual reality eye movement desensitization and reprocessing therapy for adolescents with major depressive disorder: a functional Near-Infrared spectroscopy study.European child & adolescent psychiatry · 2026Trial
- Effects of eye movement desensitisation and reprocessing on depressive symptoms, stress and rumination in adolescents with depression: a randomised controlled trial.European journal of psychotraumatology · 2025Trial
- Predictors and process moderators of EMDR therapy for depressive symptoms: protocol for a series of observational N-of-1 trials.Frontiers in psychology · 2025Article
- Telomere length and mitochondrial DNA copy number in association with trauma-focused psychotherapy efficacy.Neuroscience applied · 2025Article
- The Efficacy of Eye Movement Desensitization and Reprocessing Treatment for Depression: A Meta-Analysis and Meta-Regression of Randomized Controlled Trials.Journal of clinical medicine · 2024Review
- DNA methylation changes in association with trauma-focused psychotherapy efficacy in treatment-resistant depression patients: a prospective longitudinal study.European journal of psychotraumatology · 2024Article
- Randomized controlled trial investigating web-based, therapist delivered eye movement desensitization and reprocessing for adults with suicidal ideation.Frontiers in psychiatry · 2024Article
- Factors influencing quality of processing in EMDR therapy.Frontiers in psychology · 2024Article
- The Elephant in the Room: A Cross-Sectional Study on the Stressful Psychological Effects of the COVID-19 Pandemic in Mental Healthcare Workers.Brain sciences · 2022Article
- Effectiveness of treating depression with eye movement desensitization and reprocessing among inpatients-A follow-up study over 12 months.Frontiers in psychology · 2022Article
- Inflammation-related microRNAs are involved in stressful life events exposure and in trauma-focused psychotherapy in treatment-resistant depressed patients.European journal of psychotraumatology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The practice-based evidence suggests that it is possible to use eye movement desensitization and reprocessing (EMDR) to treat major depressive disorder (MDD), but its specific efficacy is unknown. A systematic search was carried out for randomized controlled trials comparing EMDR with a control condition group in MDD patients. Two meta-analyses were conducted, with symptom reduction as primary outcome and remission as exploratory outcome. Eight studies with 320 participants were included in this meta-analysis. The first meta-analysis showed that EMDR outperformed "No Intervention" in decreasing depressive symptoms (standardized mean difference [SMD] = -0.81, 95% CI = -1.22 to -0.39,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.