Evidence map›Paper›PMID 34421593›Full record

ArticleFrontiers in pharmacology2021

Trigonelline, An Alkaloid From

Wenhui Zhang, Yingling Zhang, Simin Chen, Hong Zhang, Man Yuan, Lianbo Xiao, Yue Lu, Hongxi Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
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  5. Frontiers in pharmacology · 2026
    Article
  6. Total alkaloids ofFrontiers in pharmacology · 2026
    Article
  7. Review
  8. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wenhui ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yingling ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Simin ChenSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hong ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Man YuanSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lianbo XiaoInstitute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Guanghua Integrative Medicine Hospital, Shanghai, China.
Yue LuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hongxi XuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shanghai University of Traditional Chinese Medicine · CNShanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trigonelline, one of the active compounds from

Indexed as

allergic asthmainflammatoryLeonurus japonicus Houttmast cellstrigonelline

Identifiers

PMID34421593
PMCPMC8371462
OpenAlexW3188333433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.