ReviewFrontiers in behavioral neuroscience2021
A Rhesus Monkey Model of Non-suicidal Self-Injury.
Review in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Euthanasia of a macaque with self-injurious behavior in a visual neuroscience laboratory.Animal advances · 2026Article
- Non-Suicidal Self-Injury: Pain Addiction Mechanisms, Neurophysiological Signatures, and Therapeutic Advances.Journal of clinical medicine research · 2025Review
- Neuroinflammation Involving Endothelin-1 and Platelet-Activating Factor Receptors Contributes To Self-Injurious Behaviors Induced by Bay k-8644 in Adolescent Mice.Neurochemical research · 2025Article
- A Study of Spontaneous Self-Injurious Behavior and Neuroimaging in Rhesus Macaques.Research (Washington, D.C.) · 2025Article
- Potential mechanisms of non-suicidal self-injury (NSSI) in major depressive disorder: a systematic review.General psychiatry · 2023Article
- Nonhuman primate abnormal behavior: Etiology, assessment, and treatment.American journal of primatology · 2022Review
- Key factors selection on adolescents with non-suicidal self-injury: A support vector machine based approach.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Non-suicidal self-injury (NSSI) is a type of behavioral pathology seen not only in a variety of clinical conditions but also among non-clinical populations, particularly adolescents and young adults. With the exception of rare genetic conditions that give rise to self-harming behaviors, the etiology of NSSI and the events that trigger specific episodes of this behavior remain poorly understood. This review presents the features of an important, extensively studied animal model of NSSI, namely spontaneously occurring self-injurious behavior (SIB) in rhesus macaque monkeys. We compare and contrast rhesus monkey SIB with NSSI with respect to form, prevalence rates, environmental and biological risk factors, behavioral correlates, proposed functions, and treatment modalities. Many parallels between rhesus monkey SIB and NSSI are demonstrated, which supports the validity of this animal model across several domains. Determining the etiology of spontaneously occurring SIB in monkeys, its underlying biological mechanisms, and which pharmacological agents are most effective for treating the disorder may aid in identifying potential risk factors for the occurrence of NSSI in humans and developing medications for severe cases that are resistant to conventional psychotherapeutic approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.