Evidence map›Paper›PMID 34421548›Full record

ReviewFrontiers in systems neuroscience2021

The Cerebellar Dopaminergic System.

Paolo Flace, Paolo Livrea, Gianpaolo Antonio Basile, Diana Galletta, Antonella Bizzoca, Gianfranco Gennarini, Salvatore Bertino, Jacopo Junio Valerio Branca, Massimo Gulisano, Simona Bianconi and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in systems neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Article
  3. Impulsivity in cerebellar ataxia: an online, multidimensional assessment.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  4. Article
  5. Transcriptomic Analysis ofBrain sciences · 2025
    Article
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  11. Article
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  14. Review
  15. Article
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  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Paolo FlaceMedical School, University of Bari 'Aldo Moro', Bari, Italy.
Paolo LivreaUniversity of Bari "Aldo Moro", Bari, Italy.
Gianpaolo Antonio BasileDepartment of Biomedical, Dental Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Diana GallettaUnit of Psychiatry and Psychology, Federico II University Hospital, Naples, Italy.
Antonella BizzocaDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.
Gianfranco GennariniDepartment of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.
Salvatore BertinoDepartment of Biomedical, Dental Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
Jacopo Junio Valerio BrancaDepartment of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy.
Massimo GulisanoDepartment of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy.
Simona BianconiPhysical, Rehabilitation Medicine and Sport Medicine Unit, University Hospital "G. Martino", Messina, Italy.
Alessia BramantiScientific Institute for Research, Hospitalization and Health Care IRCCS "Centro Neurolesi Bonino Pulejo", Messina, Italy.
Giuseppe AnastasiDepartment of Biomedical, Dental Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.
University of Bari Aldo Moro · ITUniversity of Messina · ITUniversity of Florence · ITCentro Neurolesi Bonino Pulejo · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive functions. Although the cerebellum is not been considered an elective dopaminergic region, studies attributed to it a critical role in dopamine deficit-related neurological and psychiatric disorders [e.g., Parkinson's disease (PD) and schizophrenia (SCZ)]. Data on the cerebellar dopaminergic neuronal system are still lacking. Nevertheless, biochemical studies detected in the mammalians cerebellum high dopamine levels, while chemical neuroanatomy studies revealed the presence of midbrain dopaminergic afferents to the cerebellum as well as wide distribution of the dopaminergic receptor subtypes (DRD

Indexed as

autism spectrum disorderscerebellumdopaminedopamine receptorsnon-traditional large neuronsParkinson's diseaseschizophrenia

Identifiers

PMID34421548
PMCPMC8375553
OpenAlexW3189073366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.