Evidence map›Paper›PMID 34421547›Full record

ArticleFrontiers in neural circuits2021

A Characterization of the Electrophysiological and Morphological Properties of Vasoactive Intestinal Peptide (VIP) Interneurons in the Medial Entorhinal Cortex (MEC).

Saishree Badrinarayanan, Frédéric Manseau, Sylvain Williams, Mark P Brandon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. A disinhibitory circuit mechanism explains a general principle of peak performance during mid-level arousal.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Saishree BadrinarayananDepartment of Psychiatry, Douglas Hospital Research Centre, McGill University, Montreal, QC, Canada.
Frédéric ManseauDepartment of Psychiatry, Douglas Hospital Research Centre, McGill University, Montreal, QC, Canada.
Sylvain WilliamsDepartment of Psychiatry, Douglas Hospital Research Centre, McGill University, Montreal, QC, Canada.
Mark P BrandonDepartment of Psychiatry, Douglas Hospital Research Centre, McGill University, Montreal, QC, Canada.
Douglas Mental Health University Institute · CAMcGill University · CA

Funding

CIHR 367017CIHR 377074
6 · The paper itself

Abstract

Circuit interactions within the medial entorhinal cortex (MEC) translate movement into a coherent code for spatial location. Entorhinal principal cells are subject to strong lateral inhibition, suggesting that a disinhibitory mechanism may drive their activation. Cortical Vasoactive Intestinal Peptide (VIP) expressing inhibitory neurons are known to contact other interneurons and excitatory cells and are thus capable of providing a local disinhibitory mechanism, yet little is known about this cell type in the MEC. To investigate the electrophysiological and morphological properties of VIP cells in the MEC, we use

Indexed as

Entorhinal CortexVasoactive Intestinal PeptideAction PotentialsAnimalsInterneuronsMicePatch-Clamp TechniquesVasoactive Intestinal Peptidecharacterizationinterneuronsin vitro patch clampmedial entorhinal cortexVIP interneurons

Identifiers

PMID34421547
PMCPMC8378838
OpenAlexW3184591174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.