Evidence map›Paper›PMID 34421527›Full record

ArticleFrontiers in neuroscience2021

Impact of Temporal Visual Flicker on Spatial Contrast Sensitivity in Myopia.

Jie Ye, Pawan Sinha, Fang Hou, Xianghang He, Meixiao Shen, Fan Lu, Yilei Shao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Decreasing Radial Peripapillary Capillary Perfusion Density Correlated With Visual Field Impairment in High Myopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jie YeSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Pawan SinhaDepartment of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States.
Fang HouSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Xianghang HeSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Meixiao ShenSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Fan LuSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Yilei ShaoSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNMassachusetts Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether short-term exposure to high temporal frequency full-field flicker has an impact on spatial visual acuity in individuals with varying degrees of myopia.

methodsThirty subjects (evenly divided between control and experimental groups) underwent a 5-min exposure to full-field flicker. The flicker rate was lower than critical flicker frequency (CFF) for the experimental group (12.5 Hz) and significantly higher than CFF for the controls (60 Hz). Spatial contrast sensitivity function (CSF) was measured before and immediately after flicker exposure. We examined whether the post flicker CSF parameters were different from the pre-exposure CSF values in either of the subject groups. Additionally, we examined the relationship between the amount of CSF change from pre to post timepoints and the degree of subjects' myopia. The CSF parameters included peak frequency, peak sensitivity, bandwidth, truncation, and area under log CSF (AULCSF).

resultsThere was no significant difference of all five pre-exposure CSF parameters between the two groups at baseline (

conclusionOur data suggest that exposure to perceivable high-frequency flicker (but, not to supra-CFF frequencies) enhances important aspects of spatial contrast sensitivity, and these enhancements are correlated to the degree of myopia. This finding has implications for potential interventions for cases of modest myopia.

Indexed as

flicker adaptationmyopiaspatial contrast sensitivitytemporal visual flickervisual plasticity

Identifiers

PMID34421527
PMCPMC8374145
OpenAlexW3189044236

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.