Evidence map›Paper›PMID 34421525›Full record

ArticleFrontiers in neuroscience2021

Anton V Malyshev, Iuliia A Sukhanova, Alexander S Zlobin, Vasilina R Gedzun, Vsevolod V Pavshintsev, Ekaterina V Vasileva, Arthur O Zalevsky, Igor I Doronin, Nikita A Mitkin, Andrey V Golovin and 6 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Design, Synthesis and Pharmacological Evaluation of Novel CInternational journal of molecular sciences · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Anton V MalyshevLactocore, Inc., Plymouth, MI, United States.
Iuliia A SukhanovaLactocore, Inc., Plymouth, MI, United States.
Alexander S ZlobinLactocore, Inc., Plymouth, MI, United States.
Vasilina R GedzunLactocore, Inc., Plymouth, MI, United States.
Vsevolod V PavshintsevLactocore, Inc., Plymouth, MI, United States.
Ekaterina V VasilevaFederal State Budgetary Institution, Research Zakusov Institute of Pharmacology, Moscow, Russia.
Arthur O ZalevskyShemyakin and Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia.
Igor I DoroninLactocore, Inc., Plymouth, MI, United States.
Nikita A MitkinLactocore, Inc., Plymouth, MI, United States.
Andrey V GolovinShemyakin and Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia.
Maxim L LovatDepartment of Human and Animal Physiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia.
Georgy I KovalevFederal State Budgetary Institution, Research Zakusov Institute of Pharmacology, Moscow, Russia.
Yurii A ZolotarevInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Askar R KuchumovLactocore, Inc., Plymouth, MI, United States.
Gennady A BabkinLactocore, Inc., Plymouth, MI, United States.
Bernhard LuscherDepartment of Biology, The Pennsylvania State University, University Park, PA, United States.

Funding

GABAergic Control of Depression Related Brain StatesR01MH099851 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI LUSCHER, BERNHARD · 2013 to 2019
$3.2M
NIMH NIH HHS R01 MH099851
6 · The paper itself

Abstract

The aim of the study was to develop better anxiolytics and antidepressants. We focused on GABA

Indexed as

alpha(2)delta subunitcomputational approachdrug screeningNMDA receptornovel ligandpeptide drugs

Identifiers

PMID34421525
PMCPMC8372404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.