ArticleThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2021
Enalapril and Acute Kidney Injury in a Hypertensive Premature Newborn - Should It Be Used or Not?
Article in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Kidney Volume as a Predictor and Modifier of Acute Kidney Injury with Renin-Angiotensin System Inhibitors.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Very low enalapril and enalaprilat exposureFrontiers in pharmacology · 2025Article
- Multiple Risk Factors for Heart Disease: A Challenge to the Ethnopharmacological Use ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
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Authors and funding
3 authors.
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Abstract
Extremely low birth weight infants (birth weight ≤1000 g) have a significantly lower nephron number. The glomerular filtration rate (GFR) is usually sufficient under normal conditions but is unable to meet the needs during stress, which results in acute kidney injury (AKI). We describe the case of an extremely low birth weight infant (970 g) with a gestational age of 27 weeks (immature preterm) who was mechanically ventilated because of hyaline membrane disease. AKI with anuria and a rise in serum creatinine to 3.4 mg/dL developed in the second week. Diuresis was restored after diuretics and dopamine were administered intravenously and kidney function recovered in the next two weeks. However, he slowly became hypertensive, so intravenous enalapril was introduced in the 6
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