ReviewThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2021
Sudden Unexpected Death in Epilepsy (SUDEP): A Review of Risk Factors and Possible Interventions in Children.
Review in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Medication adherence and persistence in children and adolescents with attention deficit hyperactivity disorder (ADHD): a systematic review and qualitative update.European child & adolescent psychiatry · 2025Pooled it
- Overtreatment and therapeutic nihilism in chronic epilepsy: a call to action!Acta epileptologica · 2026Review
- Sudden unexpected death in epilepsy (SUDEP): Risk management of pediatric patients with epilepsy.Epilepsia open · 2026Article
- Physical activity levels may impact on the risk of premature mortality in people with epilepsy.Nature communications · 2025Article
- Determinants of uncontrolled seizures among pediatric epilepsy patients in Debre Tabor comprehensive specialized hospitals Ethiopia.BMC pediatrics · 2025Article
- Developmental mechanisms underlying pediatric epilepsy.Frontiers in neurology · 2025Review
- Brain gray matter changes in children at risk for sudden unexpected death in epilepsy.Pediatric research · 2024Article
- A Pediatric Rat Model of Organophosphate-Induced Refractory Status Epilepticus: Characterization of Long-Term Epileptic Seizure Activity, Neurologic Dysfunction and Neurodegeneration.The Journal of pharmacology and experimental therapeutics · 2024Article
- Omega-3 Fatty Acids May Prevent Sudden Unexpected Death in Epilepsy in Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022Article
- Sudden Unexpected Death in Epilepsy (SUDEP): How Do We Prevent This Childhood Tragedy?The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022Article
- The cumulative impact of seizures: the science underlying how seizures beget seizures.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sudden unexpected death in epilepsy (SUDEP) is a serious and devastating, yet poorly understood outcome in epilepsy. This review discusses the current knowledge and understanding of SUDEP in children and adolescents. Established risk factors for SUDEP include history of generalized tonic-clonic seizures and nocturnal seizures. Other proposed risk factors include the use of multiple antiseizure medications and poor medication adherence. Possible prevention strategies for SUDEP include improved medication adherence, surgical interventions, nighttime safety, seizure detection devices, and diet. Pediatric providers have a great opportunity to educate families about SUDEP, assess medication adherence, and provide families with tools to improve medication adherence and learn about SUDEP in children and adolescents with epilepsy. Future research in SUDEP aims to further understand the etiology and risk factors of SUDEP, while developing more intervention strategies to prevent SUDEP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.