Evidence map›Paper›PMID 34421207›Full record

ArticleClinical diabetes : a publication of the American Diabetes Association2021

Identifying Potential Intervention Points for Acute Hypoglycemic Events in Patients With Type 2 Diabetes Using Retrospective Clinical Data.

Mary E Lacy, Rachel A Whitmer, Sei J Lee, Robert J Rushakoff, Mark J Pletcher

Abstract read
In one paragraph

Article in Clinical diabetes : a publication of the American Diabetes Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mary E LacyUniversity of Kentucky, Lexington, KY.ORCID https://orcid.org/0000-0002-8814-8725
Rachel A WhitmerDivision of Epidemiology, Public Health Sciences, University of California Davis School of Medicine, Davis, CA.
Sei J LeeUniversity of California, San Francisco, San Francisco, CA.
Robert J RushakoffUniversity of California, San Francisco, San Francisco, CA.
Mark J PletcherUniversity of California, San Francisco, San Francisco, CA.

Funding

Institutional Career Development CoreKL2TR001996 · NCATS · UNIVERSITY OF KENTUCKY · PI BUSH, MATTHEW LEE, KELLY, THOMAS H. · 2016 to 2025
$7.1M
Translational Epidemiology - Training for Research on Aging and Chronic diseaseT32AG049663 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Elizabeth Rose Mayeda, Mark J Pletcher · 2016 to 2026
$5.8M
Predictors of Late-life Cognitive Health in Type 1 DiabetesR01AG047500 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WHITMER, RACHEL A · 2015 to 2019
$3.0M
Developing prognostic models for life expectancy and geriatric outcomesR01AG047897 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI LEE, SEI, SMITH, ALEXANDER KELIIMOEANU · 2015 to 2018
$1.7M
Prognostic calculators for patients with Alzheimers disease and related dementiasR01AG057751 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI LEE, SEI, SMITH, ALEXANDER KELIIMOEANU · 2018 to 2021
$1.5M
NCATS NIH HHS KL2 TR001996NIA NIH HHS R01 AG047500NIA NIH HHS R01 AG047897NIA NIH HHS R01 AG057751NIA NIH HHS T32 AG049663
6 · The paper itself

Abstract

This retrospective study examined changes in medication orders as a risk factor for future acute hypoglycemic events. The investigators identified factors associated with acute hypoglycemic events resulting in emergency department visits or inpatient admissions. Non-Hispanic Black race, chronic kidney disease, insulin at baseline, and nonprivate insurance were associated with higher risk of an acute hypoglycemic event, whereas age, sex, and A1C were not. After adjustment for other risk factors, changes in insulin orders after A1C measurement were associated with a 1.5 times higher risk of an acute hypoglycemia (adjusted hazard ratio 1.48, 95% CI 1.08-2.03). These results further understanding of risk factors and clinical processes relevant to predicting and preventing acute hypoglycemia.

Identifiers

PMID34421207
PMCPMC8329018

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.