Evidence map›Paper›PMID 34421131›Full record

ArticlePattern recognition2021

Automated delineation of corneal layers on OCT images using a boundary-guided CNN.

Lei Wang, Meixiao Shen, Qian Chang, Ce Shi, Yang Chen, Yuheng Zhou, Yanchun Zhang, Jiantao Pu, Hao Chen

Open access · greenAbstract read
In one paragraph

Article in Pattern recognition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Uncertainty- and hardness-weighted loss functions for medical image segmentation.Engineering applications of artificial intelligence · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Lei WangSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Meixiao ShenSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Qian ChangSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Ce ShiSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Yang ChenKey Laboratory of Computer Network and Information Integration (Southeast University), Ministry of Education, Nanjing, China.
Yuheng ZhouSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Yanchun ZhangDepartment of Ophthalmology, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, China.
Jiantao PuDepartments of Radiology and Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Hao ChenSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Affiliated Eye Hospital of Wenzhou Medical College · CNWenzhou Medical University · CNSoutheast University · CNUniversity of Pittsburgh · USXi’an Children’s Hospital · CN

Funding

CT Assessment of Lung Fissures: Anatomy and Correlated FunctionR01HL096613 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PU, JIANTAO · 2010 to 2019
$1.9M
Macro-vasculature surrounding pulmonary nodules as a sign of malignancyR21CA197493 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PU, JIANTAO · 2016 to 2017
$370k
NCI NIH HHS R21 CA197493NHLBI NIH HHS R01 HL096613
6 · The paper itself

Abstract

Accurate segmentation of corneal layers depicted on optical coherence tomography (OCT) images is very helpful for quantitatively assessing and diagnosing corneal diseases (

Indexed as

Convolutional neural networksCorneal layersOCT imagesSegmentation

Identifiers

PMID34421131
PMCPMC8372529
OpenAlexW3181748866

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.