Evidence map›Paper›PMID 34421089›Full record

ReviewJournal of atherosclerosis and thrombosis2022

Crosstalk between Iron and Arteriosclerosis.

Yoshiro Naito, Takeshi Tsujino, Tohru Masuyama, Masaharu Ishihara

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of atherosclerosis and thrombosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yoshiro NaitoDepartment of Cardiovascular and Renal Medicine, Hyogo College of Medicine.
Takeshi TsujinoDepartment of Cardiovascular and Renal Medicine, Hyogo College of Medicine.
Tohru MasuyamaDepartment of Cardiovascular and Renal Medicine, Hyogo College of Medicine.
Masaharu IshiharaDepartment of Cardiovascular and Renal Medicine, Hyogo College of Medicine.
Hyogo Medical University · JPHoshigaoka Medical Center · JPUniversity of Health Sciences

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron is an important element for life; however, intracellular labile iron overload can lead to the generation of reactive oxygen species and cellular damage. Although iron is mainly utilized for heme synthesis and is incorporated into hemoglobin, body iron status is often implicated in the pathogenesis of cardiovascular diseases. In a cell, iron is used for basic processes such as cell growth, maintenance, and repair. Thus, iron is considered to be involved in the pathogenesis of arteriosclerosis. In fact, clinical and experimental studies have shown an association between iron and arteriosclerosis. These data suggest the crosstalk between iron and arteriosclerosis. However, iron metabolism in arteriosclerosis is often complicated, and the systemic and cellular mechanisms of iron homeostasis in arteriosclerosis remain completely unsolved. Thus, in this review, we aimed to examine the role of iron in arteriosclerosis.

Indexed as

Oxidative StressAnimalsArteriosclerosisHomeostasisHumansIron OverloadReactive Oxygen SpeciesReactive Oxygen SpeciesArteriosclerosisAtherosclerosisIronTransferrin receptor 1

Identifiers

PMID34421089
PMCPMC8894107
OpenAlexW3193714859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.