Evidence map›Paper›PMID 34420982›Full record

ArticleJournal of Parkinson's disease

Time for a New 3-D Image for Globus Pallidus Internus Deep Brain Stimulation Targeting and Programming.

Joshua K Wong, Justin D Hilliard, Vanessa M Holanda, Aysegul Gunduz, Aparna Wagle Shukla, Kelly D Foote, Michael S Okun

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Parkinson's disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Joshua K WongFixel Institute for Neurological Diseases, Department of Neurology, University of Florida, Gainesville, FL, USA.
Justin D HilliardFixel Institute for Neurological Diseases, Department of Neurosurgery, University of Florida, Gainesville, FL, USA.
Vanessa M HolandaCenter of Neurology and Neurosurgery Associates (CENNA), BP - A Beneficência Portuguesa de São Paulo, São Paulo, SP, Brazil.
Aysegul GunduzFixel Institute for Neurological Diseases, Department of Neurology, University of Florida, Gainesville, FL, USA.
Aparna Wagle ShuklaFixel Institute for Neurological Diseases, Department of Neurology, University of Florida, Gainesville, FL, USA.
Kelly D FooteFixel Institute for Neurological Diseases, Department of Neurosurgery, University of Florida, Gainesville, FL, USA.
Michael S OkunFixel Institute for Neurological Diseases, Department of Neurology, University of Florida, Gainesville, FL, USA.
University of Florida · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep brain stimulation (DBS) is an effective neuromodulatory therapy for Parkinson's disease (PD). Early studies using globus pallidus internus (GPi) DBS for PD profiled the nucleus as having two functional zones. This concept disseminated throughout the neuromodulation community as the "GPi triangle". Although our understanding of the pallidum has greatly evolved over the past 20 years, we continue to reference the triangle in our clinical decision-making process. We propose a new direction, termed the spatial boundary hypothesis, to build upon the 2-dimensional outlook on GPi DBS. We believe an updated 3-D GPi model can produce more consistent, positive patient outcomes.

Indexed as

Deep Brain StimulationGlobus PallidusParkinson DiseaseHumansImaging, Three-DimensionalTreatment OutcomeDBSDeep brain stimulationglobus pallidusGPineuromodulationParkinson’s diseasetargeting

Identifiers

PMID34420982
PMCPMC8609712
OpenAlexW3193798191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.