Evidence map›Paper›PMID 34420402›Full record

ArticleAnnals of Saudi medicine

Association of toll-like receptor 4, 5 and 10 polymorphisms with

Laith Al-Eitan, Fouad Abdelaziz Almomani, Sohaib Mahmoud Al-Khatib, Hanan Abdulraheem Aljamal, Mohammed Nayef Al-Qusami, Rawan Abdulraheem Aljamal

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pathogenicity ofWorld journal of clinical oncology · 2025
    Review
  3. New Promising Routes in Peptic Ulcers: Toll-like Receptors and Semaphorins.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laith Al-EitanFrom the Department of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.
Fouad Abdelaziz AlmomaniFrom the Department of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.
Sohaib Mahmoud Al-KhatibFrom the Department of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.
Hanan Abdulraheem AljamalFrom the Department of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.
Mohammed Nayef Al-QusamiFrom the Department of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.
Rawan Abdulraheem AljamalFrom the Department of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.
Jordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

objectiveInvestigate the susceptibility and severity of

designAnalytical, cross-sectional.

settingEndoscopy clinic at tertiary care center. PATIENTS AND

methodsGenomic DNA was extracted from formalin-fixed paraffin-embedded tissues collected from

main outcome measuresEffect of genotype distribution on SAMPLE SIZE: 250 peptic ulcer patients and 217 controls.

resultsThe

conclusionsOur findings are consistent with differences in severity of LIMITATIONS: Lack of CONFLICTS OF INTEREST: None.

Indexed as

Helicobacter InfectionsHelicobacter pyloriPeptic UlcerCross-Sectional StudiesGenetic Predisposition to DiseaseGenotypeHumansJordanPolymorphism, Single NucleotideToll-Like Receptor 10Toll-Like Receptor 4Toll-Like Receptor 5TLR10 protein, humanTLR4 protein, humanTLR5 protein, humanToll-Like Receptor 10Toll-Like Receptor 4Toll-Like Receptor 5

Identifiers

PMID34420402
PMCPMC8380278
OpenAlexW3194902465

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.