Evidence map›Paper›PMID 34420233›Full record

ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2022

Discriminative deep learning based benignity/malignancy diagnosis of dermatologic ultrasound skin lesions with pretrained artificial intelligence architecture.

Alexandra Laverde-Saad, Abdulhadi Jfri, Rubén García, Irene Salgüero, Constanza Martínez, Hirune Cembrero, Gastón Roustán, Fernando Alfageme

Abstract read
In one paragraph

Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Deep Learning-Based Skin Lesion Classification: A CNN Approach on High-Frequency Ultrasound Imaging.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Discriminative deep learning based benignity/malignancy diagnosis of dermatologic ultrasound skin lesions with pretrained artificial intelligence architecture.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
    Article
  9. Article
  10. High-Frequency Ultrasound Evaluation of Cutaneous Surgical Wound Healing: An Outpatient Experience.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra Laverde-SaadDermatology Department, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-7206-9811
Abdulhadi JfriDermatology Department, McGill University, Montreal, Quebec, Canada.
Rubén GarcíaDermatology Department, Hospital Universitario de Salamanca, Salamanca, Spain.
Irene SalgüeroDermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Constanza MartínezDermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.ORCID https://orcid.org/0000-0002-2824-4205
Hirune CembreroDermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Gastón RoustánDermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Fernando AlfagemeDermatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.ORCID https://orcid.org/0000-0002-0962-9783

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep-learning algorithms (DLAs) have been used in artificial intelligence aided ultrasonography diagnosis of thyroid and breast lesions. However, its use has not been described in the case of dermatologic ultrasound lesions. Our purpose was to train a DLA to discriminate benign form malignant lesions in dermatologic ultrasound images. MATERIALS AND

methodsWe trained a prebuilt neural network architecture (EfficientNet B4) in a commercial artificial intelligence platform (Peltarion, Stockholm, Sweden) with 235 color Doppler images of both benign and malignant ultrasound images of 235 excised and histologically confirmed skin lesions (84.3% training, 15.7% validation). An additional 35 test images were used for testing the algorithm discrimination for correct benign/malignant diagnosis. One dermatologist with more than 5 years of experience in dermatologic ultrasound blindly evaluated the same 35 test images for malignancy or benignity.

resultsEfficientNet B4 trained dermatologic ultrasound algorithm sensitivity; specificity; predictive positive values, and predicted negative values for validation algorithm were 0.8, 0.86, 0.86, and 0.8, respectively for malignancy diagnosis. When tested with 35 previously unevaluated images sets, the algorithm´s accuracy for correct benign/malignant diagnosis was 77.1%, not statistically significantly different from the dermatologist's evaluation (74.1%).

conclusionAn adequately trained algorithm, even with a limited number of images, is at least as accurate as a dermatologic-ultrasound experienced dermatologist in the evaluation of benignity/malignancy of ultrasound skin tumor images devoid of clinical data.

Indexed as

Deep LearningSkin NeoplasmsArtificial IntelligenceHumansNeural Networks, ComputerSensitivity and SpecificityUltrasonographyartificial intelligencedeep learningdermatologic ultrasoundskin ultrasound

Identifiers

PMID34420233
PMCPMC9907620

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.