Evidence map›Paper›PMID 34419517›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2022

Mobility in Older Adults Receiving Maintenance Hemodialysis: A Qualitative Study.

Christine K Liu, Janet Seo, Dayeun Lee, Kristen Wright, Manjula Kurella Tamura, Jennifer A Moye, Jonathan F Bean, Daniel E Weiner

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07033611 (Effects of Creatine Supplementation in Sarcopenic and Non-sarcopenic Patients on Chronic Hemodialysis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07033611 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Creatine Supplementation in Sarcopenic and Non-sarcopenic Patients on Chronic Hemodialysis

TypeinterventionalSponsorCarla Basualto AlarcónRan2024 to 2024Enrolled18ConditionsDialysis, Complications, Performance Enhancing Product UseArmsCreatine
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Christine K LiuSection of Geriatrics, Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California; Geriatric Research and Education Clinical Center, Veteran Affairs Palo Alto Health Care System, Palo Alto, California; Section of Geriatrics, Department of Medicine, School of Medicine, Boston University and Boston Medical Center, Boston, Massachusetts; Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts. Electronic address: chliu1@stanford.edu.
Janet SeoSection of Geriatrics, Department of Medicine, School of Medicine, Boston University and Boston Medical Center, Boston, Massachusetts; Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Dayeun LeeSection of Geriatrics, Department of Medicine, School of Medicine, Boston University and Boston Medical Center, Boston, Massachusetts; Section of Pediatric Infectious Diseases, School of Medicine, Boston University and Boston Medical Center, Boston, Massachusetts.
Kristen WrightSection of Geriatrics, Department of Medicine, School of Medicine, Boston University and Boston Medical Center, Boston, Massachusetts.
Manjula Kurella TamuraDivision of Nephrology, Stanford University School of Medicine, Stanford, California; Geriatric Research and Education Clinical Center, Veteran Affairs Palo Alto Health Care System, Palo Alto, California.
Jennifer A MoyeNew England Geriatric Research Education and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Jonathan F BeanNew England Geriatric Research Education and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, Massachusetts; Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts; Spaulding Rehabilitation Hospital, Boston, Massachusetts.
Daniel E WeinerDivision of Nephrology, Tufts Medical Center, Boston, Massachusetts.
Boston University · USHarvard University · USTufts Medical Center · USVA Palo Alto Health Care System · US

Funding

Mobility of older hemodialysis patientsK23AG057813 · NIA · STANFORD UNIVERSITY · PI LIU, CHRISTINE KEE · 2018 to 2022
$917k
A Research Mentoring Program in Geriatric Rehabilitative CareK24AG069176 · NIA · HARVARD MEDICAL SCHOOL · PI BEAN, JONATHAN F · 2020 to 2024
$661k
NIA NIH HHS K23 AG057813NIA NIH HHS K24 AG069176NIA NIH HHS L30 AG064790
6 · The paper itself

Abstract

RATIONALE &

objectiveFor older adults, maintaining mobility is a major priority, especially for those with advanced chronic diseases like kidney failure. However, our understanding of the factors affecting mobility in older adults receiving maintenance hemodialysis is limited. STUDY

designDescriptive qualitative study. SETTING &

participantsUsing purposive sampling, we recruited (1) persons aged≥60 years receiving maintenance hemodialysis; and (2) care partners (≥18 years) providing regular support to an older adult receiving hemodialysis. During a single in-person home visit, we assessed mobility using the Short Physical Performance Battery (SPPB) and conducted individual one-on-one interviews regarding important personal factors related to mobility. ANALYTICAL APPROACH: Descriptive statistics were used for demographic and SPPB data. Transcripts underwent thematic coding, informed by the International Classification of Function framework of mobility. We used conceptual content analysis to inductively extract themes and subthemes.

resultsWe enrolled 31 older adults receiving hemodialysis (42% female, 68% Black) with a mean age of 73±8 years and mean dialysis vintage of 4.6±3.5 years; their mean SPPB score was 3.6±2.8 points. Among 12 care partners (75% female, 33% Black), the mean age was 54±16 years and mean SPPB score was 10.1±2.4 points. Major themes extracted were (1) mobility represents independence; (2) mobility is precarious; (3) limitations in mobility cause distress; (4) sources of encouragement and motivation are critical; and (5) adaptability is key. LIMITATIONS: Modest sample from single geographic area.

conclusionsFor older adults receiving hemodialysis, mobility is severely limited and is often precarious in nature, causing distress. Older adults receiving hemodialysis and their care partners have identified sources of encouragement and motivation for mobility, and cite an adaptable mindset as important. Future studies should conceptualize mobility as a variable condition and build on this outlook of adaptability in the development of interventions.

Indexed as

Mobility LimitationRenal DialysisAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedQualitative ResearchAgedcaregiverscaregivingcare partnersdialysisdisabilityelderlyend-stage kidney disease (ESKD)end-stage renal disease (ESRD)gait speedgeriatricgeriatric nephrologyhemodialysiskidney replacement therapy (KRT)mobilityolderphysical functionqualitativerenal replacement therapy (RRT)Short Physical Performance Batterywalking speed

Identifiers

PMID34419517
PMCPMC8858323
OpenAlexW3195155479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.