Evidence map›Paper›PMID 34419444›Full record

ArticleExperimental eye research2021

Effects of D-serine treatment on outer retinal function.

Nathalia Torres Jimenez, Robert F Miller, Linda K McLoon

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nathalia Torres JimenezNeuroscience, University of Minnesota, Department of Neuroscience, Minneapolis, MN, USA; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
Robert F MillerNeuroscience, University of Minnesota, Department of Neuroscience, Minneapolis, MN, USA; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.
Linda K McLoonNeuroscience, University of Minnesota, Department of Neuroscience, Minneapolis, MN, USA; Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA. Electronic address: mcloo001@umn.edu.
University of Minnesota · US

Funding

Visual TestingP30EY011374 · NEI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI FERRINGTON, DEBORAH ANN · 1996 to 2019
$8.8M
Novel Immunotoxin and IGF Therapy for StrabismusR01EY015313 · NEI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MCLOON, LINDA K., MUSTARI, MICHAEL J · 2004 to 2022
$7.6M
Training Program in Translational Vision SciencesT32EY025187 · NEI · UNIVERSITY OF MINNESOTA · PI Glenn P Lobo, LINDA K. MCLOON · 2016 to 2026
$1.2M
The cell types and mechanisms of D-serine release in the postnatal retinaR21EY025027 · NEI · UNIVERSITY OF MINNESOTA · PI MILLER, ROBERT FRANCIS · 2015 to 2016
$430k
The Eye: A Window on SchizophreniaR21MH100622 · NIMH · UNIVERSITY OF MINNESOTA · PI MILLER, ROBERT FRANCIS · 2013 to 2014
$409k
pERG of SchizophreniaF31MH106296 · NIMH · UNIVERSITY OF MINNESOTA · PI TORRES JIMENEZ, NATHALIA · 2014 to 2016
$110k
NEI NIH HHS P30 EY011374NEI NIH HHS R01 EY015313NEI NIH HHS R21 EY025027NEI NIH HHS T32 EY025187NIMH NIH HHS F31 MH106296NIMH NIH HHS R21 MH100622
6 · The paper itself

Abstract

The role of the N-Methyl-D-Aspartate Receptor (NMDAR) in the outer retina is unclear despite expression of the NMDAR-complex and its subunits in the outer retina. The flash-electroretinogram (fERG) offers a non-invasive measurement of the retinal field potentials of the outer retina that can serve to clarify NMDAR contribution to early retinal processing. The role of the NMDAR in retinal function was assessed using a genetic mouse model for NMDAR hypofunction (SR

Indexed as

AnimalsElectroretinographyFemaleMaleMesopic VisionMiceMice, KnockoutPhotic StimulationRacemases and EpimerasesReceptors, N-Methyl-D-AspartateRetinaSerineSerine RacemaseRacemases and EpimerasesReceptors, N-Methyl-D-AspartateSerineSerine RacemaseA-waveB-waveD-serineElectroretinogramMesopicMice

Identifiers

PMID34419444
PMCPMC8511128
OpenAlexW3195896506

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.