ArticleJACC. Cardiovascular imaging2021
Cardiac Magnetic Resonance Assessment of Response to Cardiac Resynchronization Therapy and Programming Strategies.
Article in JACC. Cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Measuring Cardiac Dyssynchrony with DENSE (Displacement Encoding with Stimulated Echoes)-A Systematic Review.Reviews in cardiovascular medicine · 2023Pooled it
- Predictors of patient-perceived functional improvement after cardiac resynchronization therapy: a real-world multi-dimensional analysis of clinical, imaging, and ECG predictors.Frontiers in cardiovascular medicine · 2026Article
- Artificial Intelligence Performance in Cardiac Magnetic Resonance Strain Analysis for Aortic Stenosis: Validation with Echocardiography and Healthy Controls.Medicina (Kaunas, Lithuania) · 2025Article
- On the development of diagnostic support algorithms based on CPET biosignals dataPeerJ. Computer science · 2025Article
- Machine learning of ECG waveforms and cardiac magnetic resonance for response and survival after cardiac resynchronization therapy.Computers in biology and medicine · 2024Article
- Correction of phase offset errors and quantification of background noise, signal-to-noise ratio, and encoded-displacement uncertainty on DENSE MRI for kinematics of the descending thoracic and abdominal aorta.Magnetic resonance imaging · 2024Article
- Highly accelerated free-breathing real-time myocardial tagging for exercise cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Balanced Steady-State Free Precession Cine MR Imaging in the Presence of Cardiac Devices: Value of Interleaved Radial Linear Combination Acquisition With Partial Dephasing.Journal of magnetic resonance imaging : JMRI · 2023Article
- Feasibility of CMR Imaging during Biventricular Pacing: Comparison with Invasive Measurement as a Pathway towards a Novel Optimization Strategy.Journal of clinical medicine · 2023Article
- Compensation for respiratory motion-induced signal loss and phase corruption in free-breathing self-navigated cine DENSE using deep learning.Magnetic resonance in medicine · 2023Article
- Machine learning for multidimensional response and survival after cardiac resynchronization therapy using features from cardiac magnetic resonance.Heart rhythm O2 · 2022Article
- Regional left ventricular endocardial strains estimated from low-dose 4DCT: Comparison with cardiac magnetic resonance feature tracking.Medical physics · 2022Article
- Neural network methods for diagnosing patient conditions from cardiopulmonary exercise testing data.BioData mining · 2022Article
- Overview of Current Strategies Aiming at Improving Response to Cardiac Resynchronization Therapy.Anatolian journal of cardiology · 2022Article
- Patient-Specific Inverse Modeling of In Vivo Cardiovascular Mechanics with Medical Image-Derived Kinematics as Input Data: Concepts, Methods, and Applications.Applied sciences (Basel, Switzerland) · 2022Article
- Four-dimensional computed tomography of the left ventricle, Part II: Estimation of mechanical activation times.Medical physics · 2022Article
- Cardiac magnetic resonance defines mechanisms of sex-based differences in outcomes following cardiac resynchronization therapy.Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
20 authors at 1 institution in 1 country.
Funding
Abstract
objectivesThe objective was to determine the feasibility and effectiveness of cardiac magnetic resonance (CMR) cine and strain imaging before and after cardiac resynchronization therapy (CRT) for assessment of response and the optimal resynchronization pacing strategy.
backgroundCMR with cardiac implantable electronic devices can safely provide high-quality right ventricular/left ventricular (LV) ejection fraction (RVEF/LVEF) assessments and strain.
methodsCMR with cine imaging, displacement encoding with stimulated echoes for the circumferential uniformity ratio estimate with singular value decomposition (CURE-SVD) dyssynchrony parameter, and scar assessment was performed before and after CRT. Whereas the pre-CRT scan constituted a single "imaging set" with complete volumetric, strain, and scar imaging, multiple imaging sets with complete strain and volumetric data were obtained during the post-CRT scan for biventricular pacing (BIVP), LV pacing (LVP), and asynchronous atrial pacing modes by reprogramming the device outside the scanner between imaging sets.
results100 CMRs with a total of 162 imaging sets were performed in 50 patients (median age 70 years [IQR: 50-86 years]; 48% female). Reduction in LV end-diastolic volumes (P = 0.002) independent of CRT pacing were more prominent than corresponding reductions in right ventricular end-diastolic volumes (P = 0.16). A clear dependence of the optimal CRT pacing mode (BIVP vs LVP) on the PR interval (P = 0.0006) was demonstrated. The LVEF and RVEF improved more with BIVP than LVP with PR intervals ≥240 milliseconds (P = 0.025 and P = 0.002, respectively); the optimal mode (BIVP vs LVP) was variable with PR intervals <240 milliseconds. A lower pre-CRT displacement encoding with stimulated echoes (DENSE) CURE-SVD was associated with greater improvements in the post-CRT CURE-SVD (r = -0.69; P < 0.001), LV end-systolic volume (r = -0.58; P < 0.001), and LVEF (r = -0.52; P < 0.001).
conclusionsCMR evaluation with assessment of multiple pacing modes during a single scan after CRT is feasible and provides useful information for patient care with respect to response and the optimal pacing strategy.
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