Evidence map›Paper›PMID 34419372›Full record

ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2021

Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.

Lorriana E Leard, Are M Holm, Maryam Valapour, Allan R Glanville, Sandeep Attawar, Meghan Aversa, Silvia V Campos, Lillian M Christon, Marcelo Cypel, Göran Dellgren and 14 more

2 registry-linked trialsOpen access · hybridAbstract readConsensus Statement
In one paragraph

Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 375 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
375citing papers in PubMed, 1 pooled it
100.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05135156 nacompletednot on this map

Lung Transplant Resources for Education and Decision-making for Your Cystic Fibrosis (READY): A Pilot Randomized Controlled Trial

TypeinterventionalSponsorUniversity of WashingtonRan2021 to 2022Enrolled52ConditionsCystic FibrosisArmsInvestigator-designed lung transplant education resource (Research Intervention), Publicly available transplant education resource (Attention Control)
NCT05195853 unknown statusnot on this mapstarted 2022, after this paper: background citation

Optimization of Donor-Recipient Matching in Lung Transplantation

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2022 to 2023Enrolled500ConditionsLung Transplant
3 · Its place in the literature

Who cites it

375 citing papers in PubMed, 1 synthesis or guideline pooled it, 699 citations in OpenAlex.

  1. Guideline
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  3. Review
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  9. Article
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  11. Review
  12. Single versus double lung transplantation in patients with pneumoconiosis: a retrospective cohort study.Journal of occupational medicine and toxicology (London, England) · 2026
    Article
  13. Anellovirus-mediated interferon dysregulation enhances virus-induced lung injury.American journal of respiratory cell and molecular biology · 2026
    Article
  14. Pulmonary [European journal of nuclear medicine and molecular imaging · 2026
    Article
  15. Article
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  17. Article
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  19. Review
  20. Article

315 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 10 countries.

Lorriana E LeardUniversity of California San Francisco, California. Electronic address: Lorriana.Leard@ucsf.edu.
Are M HolmOslo University Hospital, Oslo, Norway.
Maryam ValapourCleveland Clinic, Ohio.
Allan R GlanvilleSt. Vincent's Hospital, New South Wales, Australia.
Sandeep AttawarKrishna Institute of Medical Sciences Institute for Heart and Lung Transplantation, Hyderabad, India.
Meghan AversaUniversity of Toronto, Ontario, Canada.
Silvia V CamposHeart Institute (InCor) University of Sao Paulo Medical School, Sao Paulo, Brazil.
Lillian M ChristonMedical University of South Carolina, South Carolina.
Marcelo CypelUniversity of Toronto, Ontario, Canada.
Göran DellgrenSahlgrenska University Hospital and University of Gothenburg, Sweden.
Matthew G HartwigDuke University, North Carolina.
Siddhartha G KapnadakUniversity of Washington, Washington.
Nicholas A KolaitisUniversity of California San Francisco, California.
Robert M KotloffUniversity of Pennsylvania, Pennsylvania.
Caroline M PattersonRoyal Papworth Hospital, Cambridge, UK.
Oksana A ShlobinInova Fairfax Hospital, Virginia.
Patrick J SmithDuke University, North Carolina.
Amparo SoléUniversity Hospital La Fe, Valencia, Spain.
Melinda SolomonHospital for Sick Children, University of Toronto, Ontario, Canada.
David WeillWeill Consulting Group, New Orleans, Louisiana.
Marlies S WijsenbeekErasmus MC, University Medical Center Rotterdam, The Netherlands.
Brigitte W M WillemseBeatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Selim M ArcasoyColumbia University, New York, New York.
Kathleen J RamosUniversity of Washington, Washington.
Duke University · USUniversity of Toronto · CAUniversity of Washington · USCalifornia University of Pennsylvania · USCleveland Clinic · USColumbia University · USErasmus MC · NLHospital Universitari i Politècnic La Fe · ESInova Fairfax Hospital · USKrishna Institute of Medical Sciences · INLear (United States) · USMedical University of South Carolina · USOslo University Hospital · NOPapworth Hospital · GBSahlgrenska University Hospital · SESickKids Foundation · CASt Vincent's Hospital · AUUniversidade de São Paulo · BRUniversity Medical Center Groningen · NLUniversity of California, San Francisco · US

Funding

Predicting survival and planning for lung transplantation in severe cystic fibrosisK23HL138154 · NHLBI · UNIVERSITY OF WASHINGTON · PI RAMOS, KATHLEEN JESSICA · 2017 to 2021
$947k
NHLBI NIH HHS K23 HL138154
6 · The paper itself

Abstract

Tens of thousands of patients with advanced lung diseases may be eligible to be considered as potential candidates for lung transplant around the world each year. The timing of referral, evaluation, determination of candidacy, and listing of candidates continues to pose challenges and even ethical dilemmas. To address these challenges, the International Society for Heart and Lung Transplantation appointed an international group of members to review the literature, to consider recent advances in the management of advanced lung diseases, and to update prior consensus documents on the selection of lung transplant candidates. The purpose of this updated consensus document is to assist providers throughout the world who are caring for patients with pulmonary disease to identify potential candidates for lung transplant, to optimize the timing of the referral of these patients to lung transplant centers, and to provide transplant centers with a framework for evaluating and selecting candidates. In addition to addressing general considerations and providing disease specific recommendations for referral and listing, this updated consensus document includes an ethical framework, a recognition of the variability in acceptance of risk between transplant centers, and establishes a system to account for how a combination of risk factors may be taken into consideration in candidate selection for lung transplantation.

Indexed as

Patient SelectionSocieties, MedicalContraindicationsCystic FibrosisHumansLung TransplantationPulmonary Disease, Chronic Obstructivechronic obstructive pulmonary diseaseconsensuscystic fibrosisemphysemaethicsinterstitial lung diseaselung transplantpulmonary hypertensionrisk factor

Identifiers

PMID34419372
PMCPMC8979471
OpenAlexW3183806681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.