Evidence map›Paper›PMID 34418986›Full record

ArticleBMC cancer2021

Multiple myeloma in Armenia during the period 2006-2018: facts and discussion.

Narine Ghazaryan, Samvel Danelyan, Samvel Bardakhchyan, Anahit Saharyan, Lusine Sahakyan

Abstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Narine GhazaryanArmenian Haematology Center Aft.Prof. R.Yeolyan, Yerevan, Armenia. naringhazaryan@gmail.com.
Samvel DanelyanArmenian Haematology Center Aft.Prof. R.Yeolyan, Yerevan, Armenia.
Samvel BardakhchyanArmenian Haematology Center Aft.Prof. R.Yeolyan, Yerevan, Armenia.
Anahit SaharyanYerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia.
Lusine SahakyanArmenian Haematology Center Aft.Prof. R.Yeolyan, Yerevan, Armenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is known that one of the reasons for the increased incidence of hematological malignancies is caused by the growth of multiple myeloma (MM). Worldwide, approximately 159,985 new cases of MM are diagnosed representing 0.9% of all cancer diagnoses and 106,105 patients will die from MM accounting for 1.1% of all cancer deaths per year. Despite significant advances in the MM treatment the mortality rates are still high. The presented study is the first accurate epidemiological study of ММ in Armenia for the period of 2006-2018.

methodsThe initial data for this retrospective cohort survey were derived from ambulance cards, hospitalization journals, and clinical data from the Registry of Blood Diseases at the Yeolyan Hematology Center.

resultsData analysis showed that during 2006-2018 the average annual incidence for the MM was 1.2 per 100,000 population. A significant increase was observed in 2018 compared to 2006, 1.9 vs. 0.7 per 100,000 population. Interestingly, there were no sex differences in the overall MM incidence during the study period. According to the received data, during the period of the 2006-2009 and 2014-2018 the 1-year survival rate for both sexes decreased dramatically from 83 to 64.1% at age group 60 years and below and from 78.5 to 68.1% in group 60 years and over. The 1-year overall survival (OS) for both sexes decreased by 18.9% for patients (≤60 age group) and 10.4% (> 60 age group) in the period of 2006-2009 to the period of 2014-2018.

conclusionsThe incidence rates for the MM increased during the analyzed period. Our study showed that males and females in the age group 60 years and below had better 5-year overall survival compared to elder ones and females have better survival.

Indexed as

AdultAgedArmeniaFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedMultiple MyelomaPopulation GroupsPrognosisRegistriesRetrospective StudiesSurvival RateTime FactorsArmeniaIncidenceMultiple myelomaSurvival

Identifiers

PMID34418986
PMCPMC8379877

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.