Evidence map›Paper›PMID 34418873›Full record

ArticleClinical imaging2021

FDG PET/CT imaging features and clinical utility in COVID-19.

Randy Yeh, Ahmed Elsakka, Rick Wray, Rocio Perez Johnston, Natalie C Gangai, Hooman Yarmohammadi, Heiko Schoder, Neeta Pandit-Taskar

Open access · bronzeAbstract read
In one paragraph

Article in Clinical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Randy YehMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America. Electronic address: yehr@mskcc.org.
Ahmed ElsakkaMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America; Interventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Rick WrayMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Rocio Perez JohnstonBody Imaging Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Natalie C GangaiBody Imaging Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Hooman YarmohammadiInterventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Heiko SchoderMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Neeta Pandit-TaskarMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, United States of America.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeTo determine the imaging findings and potential clinical utility of FDG PET/CT in patients with laboratory-confirmed COVID-19.

methodsWe performed a single institution retrospective review of patients diagnosed with COVID-19 using real time reverse transcription-polymerase chain reaction (RT-PCR) who underwent FDG PET/CT for routine cancer care between March 1, 2020 to April 30, 2020, during the height of the pandemic in New York City, New York, United States. PET/CT scans were retrospectively reviewed for imaging findings suspicious for COVID-19. For positive scans, PET and CT findings were recorded, including location, FDG avidity (SUV

resultsThirty-one patients (21 males and 10 females, mean age 57 years ± 16) were evaluated. Thirteen of 31 patients had positive PET/CT scans, yielding a detection rate of 41.9%. Patients with positive scans had significantly higher rates of symptomatic COVID-19 infection (77% vs 28%, p = 0.01) and hospitalizations (46% vs. 0%, p = 0.002) compared to patients with negative scans. Eleven of 13 patients (84.6%) with positive scans had FDG-avid lung findings, with mean lung SUV

conclusionFDG PET/CT has limited sensitivity for detecting COVID-19 infection. However, a positive PET scan is associated with higher risk of symptomatic infection and hospitalizations, which may be helpful in predicting disease severity.

Indexed as

COVID-19Positron Emission Tomography Computed TomographyFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedNew York CityPositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesSARS-CoV-2Fluorodeoxyglucose F18RadiopharmaceuticalsCoronavirus disease 2019Covid-19FDG PETPET/CT

Identifiers

PMID34418873
PMCPMC8349436
OpenAlexW3189369722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.