Evidence map›Paper›PMID 34418167›Full record

ArticleJournal of clinical laboratory analysis2021

A rare case of pulmonary nocardiosis comorbid with Sjogren's syndrome.

Yumeng Peng, Xiaoyan Dong, Yongze Zhu, Huoyang Lv, Yumei Ge

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Successful Treatment of HIV-Combined CNSInfection and drug resistance · 2025
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  4. Article
  5. Molecular detection of Nocardia: development and application of a real-time PCR assay in sputum and bronchoalveolar lavage fluid samples.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  6. World journal of clinical cases · 2023
    Article
  7. Pacemaker AssociatedInfection and drug resistance · 2023
    Article
  8. A Rare Case of a Subcutaneous Abscess Caused byInfection and drug resistance · 2023
    Article
  9. Primary Sjögren's syndrome combined withArchives of medical science : AMS · 2022
    Article
  10. A rare case of pulmonary nocardiosis comorbid with Sjogren's syndrome.Journal of clinical laboratory analysis · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yumeng PengCenter of Clinical Laboratory Medicine, the Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Xiaoyan DongThe Second Medical College, Zhejiang Chinese Medical University, Zhejiang, China.
Yongze ZhuCenter of Clinical Laboratory Medicine, the Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Huoyang LvCenter of Clinical Laboratory Medicine, the Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.
Yumei GeCenter of Clinical Laboratory Medicine, the Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, China.ORCID https://orcid.org/0000-0003-3321-2176
Zhejiang Provincial People's Hospital · CNBengbu Medical College · CNZhejiang Chinese Medical University · CN

Funding

the National Natural Science Foundation of China 81802021the Research Initiation Fund of Zhejiang People's Hospital in China ZRY2018B004Zhejiang Medical and Health Science and Technology Project of China 2019KY013Zhejiang Medical and Health Science and Technology Project of China 2021KY022Zhejiang Provincial Natural Science Fund LY20H200008
6 · The paper itself

Abstract

backgroundNocardia is an opportunistic pathogen, which occurs in patients with autoimmune diseases and immune dysfunction, and can cause bacteremia and other life-threatening complications. The clinical manifestations of Nocardia pneumonia are similar to tuberculous and other clinical common bacterial pneumonia, but its antibacterial treatments are different and detection methods are unique, which may lead patients to suffer for many years due to clinical misdiagnosis and missed diagnosis.

methodsImaging and laboratory examinations were performed for preliminary diagnosis, and next-generation sequencing was used to identify the exact species type of Nocardia in the bronchoalveolar lavage fluid (BALF) of the patient.

resultsImaging and laboratory parameters preliminarily implied that the patient was infected with Nocardia with Sjogren's syndrome (SS), and NGS showed that the strain was N. terpenica.

conclusionsAccurate etiological diagnosis and corresponding antibiotics are key to improve the prognosis of pulmonary nocardiosis in this case. Nocardia pneumonia is rare in clinical practice; it is of great medical significance to improve the understanding of pulmonary nocardiosis.

Indexed as

AgedAnti-Bacterial AgentsHigh-Throughput Nucleotide SequencingHumansMaleNocardiaNocardia InfectionsSjogren's SyndromeAnti-Bacterial Agentsetiological examinationnext-generation sequencingNocardia terpenicapneumoniaSjogren's syndrome

Identifiers

PMID34418167
PMCPMC8418472
OpenAlexW3194508790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.