Evidence map›Paper›PMID 34417964›Full record

ArticleJournal of natural medicines2022

New monoterpenoids from the stigmas of Crocus sativus.

Qing-Wei Fang, Wen-Wei Fu, Jin-Ling Yang, Yue Lu, Jiang-Cheng Chen, Pei-Ying Wu, Xue Zhang, Hong-Xi Xu

Abstract read
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In one paragraph

Article in Journal of natural medicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qing-Wei Fang *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cai Lun Lu 1200, Shanghai, 201203, People's Republic of China.
Wen-Wei Fu *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cai Lun Lu 1200, Shanghai, 201203, People's Republic of China. fu_wenwei@163.com.
Jin-Ling YangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cai Lun Lu 1200, Shanghai, 201203, People's Republic of China.
Yue LuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cai Lun Lu 1200, Shanghai, 201203, People's Republic of China.
Jiang-Cheng ChenSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cai Lun Lu 1200, Shanghai, 201203, People's Republic of China.
Pei-Ying WuSaffron Div. of Shanghai Traditional Chinese Medicine Co., Ltd, Shanghai, 200002, People's Republic of China.
Xue ZhangSaffron Div. of Shanghai Traditional Chinese Medicine Co., Ltd, Shanghai, 200002, People's Republic of China.
Hong-Xi XuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Cai Lun Lu 1200, Shanghai, 201203, People's Republic of China. xuhongxi88@gmail.com.

Funding

Education and Scientific Research Project of Shanghai ZY (2018-2020)-CCCX-2001-02)Key-Area Research and Development Program of GuangDong Province 2020B1111110003Key Technologies Research and Development Program 2019ZX09301140
6 · The paper itself

Abstract

One new compound, crocusatin M (1), and three new glycosidic compounds, crocusatins N-P (2-4), along with nine known compounds were isolated from the dried stigmas of Crocus sativus. The structures of new compounds were elucidated on the basis of spectroscopic analysis, and the absolute configurations of 1, 2, and 3 were unambiguously assigned by the comparison of experimental and calculated ECD data. This is the first report of the isolation of 4 with the HMG moiety from the genus Crocus. Compounds 1 and 4 exhibited weak anti-inflammatory activities on inhibiting lipopolysaccharide (LPS)-induced NO production.

Indexed as

CrocusAnti-Inflammatory AgentsFlowersMonoterpenesPhytochemicalsAnti-Inflammatory AgentsMonoterpenesPhytochemicalsAnti-inflammation activityCrocus sativusMonoterpenoidsStructure elucidation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.