Evidence map›Paper›PMID 34417945›Full record

ArticleJournal of thrombosis and thrombolysis2022

Efficacy of a hypolipid diet in patients with primary antiphospholipid syndrome with dyslipidemia: a prospective study.

Thays C R Rodrigues, Camila de Oliveira Vaz, Eliana C M Miranda, Marcos Pereira, Sabrina da Silva Saraiva, Joyce Maria Annichino-Bizzacchi, Bruna de Moraes Mazetto, Fernanda A Orsi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Thays C R RodriguesHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Camila de Oliveira VazHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Eliana C M MirandaHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Marcos PereiraHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Sabrina da Silva SaraivaHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Joyce Maria Annichino-BizzacchiHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Bruna de Moraes MazettoHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.
Fernanda A OrsiHematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil. ferorsi@unicamp.br.ORCID http://orcid.org/0000-0002-7908-9073
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/14172-6
6 · The paper itself

Abstract

Although dyslipidemia is associated with poorer prognosis in antiphospholipid syndrome (APS), the management of lipid disorders can be challenging. While statins may increase the bleeding risk associated with anticoagulation, the effectiveness of hypolipid diet (HD) has not yet been established in patients with autoimmune disorders. In this study, we evaluated whether HD is associated with decreases in cholesterol levels in patients with thrombotic primary APS (t-PAPS) and dyslipidemia. Nutritional and lipid profiles were assessed before HD was initiated (baseline) and after 3 and 6 months with HD. A 24-h dietary recall was applied to assess the adherence to the diet. Forty-four patients were included, mean age was 43 years (± 12.93) and 65% were female. After HD was started, the intake of carbohydrates, lipids, saturated fats and cholesterol decreased, whereas dietary fiber intake increased. Levels of total cholesterol (TC) and non-high density lipoprotein cholesterol (non-HDL-C) decreased after 3 and 6 months of HD, as compared to baseline (P = 0.007 and P = 0.008). Low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) values did not change during the study period. The mean body mass index (BMI) decreased from 28.4 to 27.8 kg/m

Indexed as

Antiphospholipid SyndromeDyslipidemiasAdultCholesterol, HDLDietFemaleHumansLipidsProspective StudiesCholesterol, HDLLipidsAntiphospholipid syndromeAtherosclerosisCardiovascular riskDiet therapyDyslipidemiaHypolipid diet

Identifiers

PMID34417945
PMCPMC8904340
OpenAlexW3193938564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.