Evidence map›Paper›PMID 34417930›Full record

ReviewJournal, genetic engineering & biotechnology2021

GABA

Amr Ghit, Dina Assal, Ahmed S Al-Shami, Diaa Eldin E Hussein

Open access · diamondAbstract readReview
In one paragraph

Review in Journal, genetic engineering & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 202 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed, 3 pooled it
25.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

202 citing papers in PubMed, 3 syntheses or guidelines pooled it, 367 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Use of Drugs Affecting GABAMolecular neurobiology · 2025
    Pooled it
  4. Trial
  5. Hederagenin Attenuates Morphine Addiction via GABAA1-Mediated Modulation of CaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. GABASynapse (New York, N.Y.) · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. A pore-facing glycan constrains GABACommunications biology · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

142 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Amr GhitDepartment of Biology and Biotechnology, University of Pavia, Pavia, Italy. amr.saadshehatariz01@universitadipavia.it.ORCID http://orcid.org/0000-0002-7153-2413
Dina AssalDepartment of Biotechnology, American University in Cairo (AUC), Cairo, Egypt.ORCID https://orcid.org/0000-0002-5967-2528
Ahmed S Al-ShamiDepartment of Biotechnology, Institute of Graduate Studies and Research (IGSR), Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0003-1979-3883
Diaa Eldin E HusseinAnimal Health Research Institute (AHRI), Agricultural Research Center (ARC), Port of Alexandria, Alexandria, Egypt.ORCID https://orcid.org/0000-0001-9428-3221
Agricultural Research Center · EGAlexandria University · EGAmerican University in Cairo · EGUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundγ-Aminobutyric acid sub-type A receptors (GABA MAIN BODY: GABA

conclusionTo date, few reviews have discussed GABA

Indexed as

Allosteric modulationAlzheimer’s diseaseAutism spectrum disorderBarbituratesBenzodiazepineEpilepsyGABAGABAARSchizophrenia

Identifiers

PMID34417930
PMCPMC8380214
OpenAlexW3196174803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.