Evidence map›Paper›PMID 34417920›Full record

Trial reportAIDS and behavior2022

Social Influence and Uptake of Couples HIV Testing and Counselling in KwaZulu-Natal, South Africa.

Matthew J Johnson, Lynae A Darbes, Victoria Hosegood, Mallory O Johnson, Katherine Fritz, Thulani Ngubane, Heidi van Rooyen, Nuala McGrath

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew J JohnsonMRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Mailpoint 95, Tremona Road, Southampton, SO16 6YD, UK. mj2@mrc.soton.ac.uk.ORCID http://orcid.org/0000-0001-5597-6615
Lynae A DarbesCenter for AIDS Prevention Studies, Division of Prevention Sciences, School of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Victoria HosegoodDepartment of Social Statistics and Demography, Faculty of Social, Human and Mathematical Sciences, University of Southampton, Southampton, UK.
Mallory O JohnsonCenter for AIDS Prevention Studies, Division of Prevention Sciences, School of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Katherine FritzInternational Center for Research on Women, Washington, DC, USA.
Thulani NgubaneHuman Sciences Research Council, Durban, South Africa.
Heidi van RooyenHuman Sciences Research Council, Durban, South Africa.
Nuala McGrathDepartment of Social Statistics and Demography, Faculty of Social, Human and Mathematical Sciences, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0002-1039-0159

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Couples in Context: An RCT of a Couples-based HIV Prevention InterventionR01MH086346 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DARBES, LYNAE A · 2010 to 2014
$2.5M
Economic and Social Research Council ES/J021202/1National Institute for Health Research RP-2017-08-ST2-008NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH086346Wellcome TrustWellcome Trust WT083495MA
6 · The paper itself

Abstract

Social influences may create a barrier to couples HIV testing and counselling (CHTC) uptake in sub-Saharan Africa. This secondary analysis of data collected in the 'Uthando Lwethu' randomised controlled trial used discrete-time survival models to evaluate the association between within-couple average 'peer support' score and uptake of CHTC by the end of nine months' follow-up. Peer support was conceptualised by self-rated strength of agreement with two statements describing friendships outside of the primary partnership. Eighty-eight couples (26.9%) took up CHTC. Results tended towards a dichotomous trend in models adjusted only for trial arm, with uptake significantly less likely amongst couples in the higher of four peer support score categories (OR 0.34, 95% CI 0.18, 0.68 [7-10 points]; OR 0.53, 95% CI 0.28, 0.99 [≥ 11 points]). A similar trend remained in the final multivariable model, but was no longer significant (AOR 0.59, 95% CI 0.25, 1.42 [7-10 points]; AOR 0.88, 95% CI 0.36, 2.10 [≥ 11 points]). Accounting for social influences in the design of couples-focused interventions may increase their success.

Indexed as

HIV InfectionsSexual PartnersCounselingHIV TestingHumansSouth AfricaCouples HIV testing and counsellingHIV preventionPeer supportSocial influenceSouth Africa

Identifiers

PMID34417920
PMCPMC8840905

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.