Evidence map›Paper›PMID 34417874›Full record

ArticleArchives of virology2021

Human astrovirus types 1, 4 and 5 circulating among children with acute gastroenteritis in a rural Brazilian state, 2010-2016.

Adriana Luchs, Kaelan Tardy, Roozbeh Tahmasebi, Simone Guadagnucci Morillo, Flavio Augusto de Pádua Milagres, Vanessa Dos Santos Morais, Rafael Brustulin, Maria da Aparecida Rodrigues Teles, Lais Sampaio de Azevedo, Ellen Viana de Souza and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Adriana LuchsInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, Av. Dr Arnaldo, nº 355, São Paulo, SP, 01246-902, Brazil. driluchs@gmail.com.ORCID http://orcid.org/0000-0003-4131-990X
Kaelan Tardy *Instituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, nº 470, São Paulo, SP, 05403-000, Brazil.
Roozbeh TahmasebiInstituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, nº 470, São Paulo, SP, 05403-000, Brazil.
Simone Guadagnucci MorilloInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, Av. Dr Arnaldo, nº 355, São Paulo, SP, 01246-902, Brazil.
Flavio Augusto de Pádua MilagresUniversidade Federal do Tocantins, Tocantins, Brazil.
Vanessa Dos Santos MoraisInstituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, nº 470, São Paulo, SP, 05403-000, Brazil.
Rafael BrustulinUniversidade Federal do Tocantins, Tocantins, Brazil.
Maria da Aparecida Rodrigues TelesLaboratório Central de Saúde Pública do Tocantins (Lacen-TO), Tocantins, Brazil.
Lais Sampaio de AzevedoInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, Av. Dr Arnaldo, nº 355, São Paulo, SP, 01246-902, Brazil.
Ellen Viana de SouzaInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, Av. Dr Arnaldo, nº 355, São Paulo, SP, 01246-902, Brazil.
Roberta Salzone MedeirosInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, Av. Dr Arnaldo, nº 355, São Paulo, SP, 01246-902, Brazil.
Yasmin França Viana Pires de SouzaInstituto Adolfo Lutz, Centro de Virologia, Núcleo de Doenças Entéricas, Av. Dr Arnaldo, nº 355, São Paulo, SP, 01246-902, Brazil.
Emerson Luiz Lima AraújoCoordenação Geral de Laboratórios de Saúde Pública, Departamento de Articulação Estratégica de Vigilância em Saúde da Secretaria de Vigilância em Saúde do Ministério da Saúde do Brasil (CGLAB/DAEVS/SVS-MS), Brasília, Brazil.
Steven S WitkinInstituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, nº 470, São Paulo, SP, 05403-000, Brazil.
Xutao DengVitalant Research Institute, San Francisco, USA.
Eric Delwart *Vitalant Research Institute, San Francisco, USA.
Ester Cerdeira Sabino *Instituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, nº 470, São Paulo, SP, 05403-000, Brazil.
Elcio Leal *Instituto de Ciências Biológicas, Universidade Federal do Pará, Pará, Brazil.
Antonio Charlys da Costa *Instituto de Medicina Tropical, Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, nº 470, São Paulo, SP, 05403-000, Brazil. charlysbr@yahoo.com.br.
Instituto Adolfo Lutz · BRUniversidade de São Paulo · BRUniversidade Federal do Tocantins · BRUniversity of California, San Francisco · USMinistério da Saúde · BRUniversidade do Tocantins · BRUniversidade Federal do Pará · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 400354/2016-0Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR) 302677/2019-4Fundação de Amparo à Pesquisa do Estado de Alagoas (BR) 2020/11182-6Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2015/12944-9Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2016/01735-2Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2017/00021-9Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2019/21706-5Fundação de Amparo à Pesquisa do Estado de São Paulo (BR) 2020/02469-0
6 · The paper itself

Abstract

This study combined conventional epidemiology of human astroviruses. From 2010 to 2016, 232 stool samples from children under 5 years of age were screened using NGS and conventional RT-PCR followed by genetic analysis in order to investigate the genotypic diversity of classical human astrovirus (HAstV) circulating in Tocantins State, Brazil. HAstV was detected in 16 cases (6.9%). Seven specimens (43.7%; 7/16) were positive according RT-PCR and next-generation sequencing (NGS) to investigate the molecular to both NGS and RT-PCR. NGS and RT-PCR individually revealed six (37.5%; 6/16) and three (18.8%; 3/16) additional positive samples, respectively. Sequencing of the HAstV-positive samples revealed HAstV-1a (9/16), HAstV-4c (3/16), and HAstV-5c (4/16) lineages.

Indexed as

Astroviridae InfectionsBrazilChild, PreschoolFecesFemaleGastroenteritisGenome, ViralHigh-Throughput Nucleotide SequencingHumansInfantInfant, NewbornMaleMamastrovirusPhylogenyRural Population

Identifiers

PMID34417874
OpenAlexW3195902781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.