Evidence map›Paper›PMID 34417870›Full record

ReviewJournal of neurology2022

A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value.

Giuseppe Cosentino, Micol Avenali, Antonio Schindler, Nicole Pizzorni, Cristina Montomoli, Giovanni Abbruzzese, Angelo Antonini, Filippo Barbiera, Marco Benazzo, Eduardo Elias Benarroch and 28 more

Registry-linked trialOpen access · hybridAbstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05898139 (Describe to Better Understand, the Mealtime of People With Parkinson's Disease Dependent on Food Intake), which is not on this map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05898139 completednot on this mapstarted 2024, after this paper: background citation

Describe to Better Understand, the Mealtime of People With Parkinson's Disease Dependent on Food Intake

TypeobservationalSponsorUniversity Hospital, ToulouseRan2024 to 2025Enrolled22ConditionsParkinson Disease, Deglutition Disorders
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Patterns of spontaneous saliva swallowings during awake and sleep states in Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  8. Review
  9. Article
  10. Review
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  14. Neurorehabilitation Clinical Pathways in Stroke: The Padova Model.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 6 countries.

Giuseppe Cosentino *Department of Brain and Behavioral Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy.
Micol Avenali *Department of Brain and Behavioral Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy. micol.avenali@mondino.it.ORCID http://orcid.org/0000-0002-7880-9921
Antonio SchindlerDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Milan, Italy.
Nicole PizzorniDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Milan, Italy.
Cristina MontomoliDepartment of Public Health, Experimental and Forensic Medicine, Unit of Biostatistics and Clinical Epidemiology, University of Pavia, Pavia, Italy.
Giovanni AbbruzzeseDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genoa-IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Angelo AntoniniParkinson and Movement Disorders Unit, Department of Neuroscience, University of Padua, Padua, Italy.
Filippo BarbieraAzienda Sanitaria Provinciale Agrigento-UO Complessa Radiologia Distretto Ag 2 Sciacca-Ribera. Presidio Ospedaliero di Sciacca (AG), Sciacca, Agrigento, Italy.
Marco BenazzoDepartment of Otolaryngology Head Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Eduardo Elias BenarrochDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Giulia BertinoDepartment of Otolaryngology Head Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Emanuele CeredaClinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Pere ClavèGastrointestinal Physiology Laboratory, Hospital de Mataró, Universitat Autónoma de Barcelona, Mataró, Spain.
Pietro CortelliIRCCS Istituto di Scienze Neurologiche, Bologna, Italy.
Roberto EleopraFondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Chiara FerrariDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Milan, Italy.
Shaheen HamdyDivision of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Salford Royal Hospital, Salford, UK.
Maggie-Lee HuckabeeDepartment of Communication Disorders, Rose Centre for Stroke Recovery and Research, University of Canterbury, Christchurch, New Zealand.
Leonardo LopianoDepartment of Neuroscience "Rita Levi Montalcini", University of Torino, Turin, Italy.
Rosario Marchese RagonaENT Department, University of Padova, Padua, Italy.
Stefano MasieroRehabilitation Unit, Department of Neuroscience, University of Padova, Padua, Italy.
Emilia MichouDepartment of Speech and Language Therapy, School of Health Rehabilitation Sciences, University of Patras, Patras, Greece.
Antonio OcchiniDepartment of Otolaryngology Head Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
Claudio PacchettiParkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy.
Ronald F PfeifferDepartment of Neurology, Oregon Health and Science University, Portland, OR, USA.
Domenico A RestivoDepartment of Neurology, Garibaldi Hospital, Catania, Italy.
Mariangela RondanelliDepartment of Public Health, Experimental and Forensic Medicine, Unit of Human and Clinical Nutrition, University of Pavia, IRCCS Mondino Foundation, Pavia, Italy.
Giovanni RuoppoloDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
Giorgio SandriniDepartment of Brain and Behavioral Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy.
Anthony H V SchapiraDepartment of Clinical and Movement Neurosciences, UCL, Queen Square Institute of Neurology, London, UK.
Fabrizio StocchiUniversity and Institute for Research and Medical Care IRCCS San Raffaele, Rome, Italy.
Eduardo TolosaParkinson Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED:CB06/05/0018-ISCIII), University of Barcelona, Barcelona, Spain.
Francesca ValentinoParkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy.
Mauro ZamboniDepartment of Medicine, Division of Geriatrics, Healthy Aging Center, University of Verona, Verona, Italy.
Roberta ZangagliaParkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy.
Mario ZappiaDepartment GF Ingrassia, University of Catania, Catania, Italy.
Cristina TassorelliDepartment of Brain and Behavioral Sciences, University of Pavia, Via Mondino 2, 27100, Pavia, Italy.
Enrico AlfonsiClinical Neurophysiology Unit, IRCCS Mondino Foundation, Pavia, Italy.
University of Pavia · ITUniversity of Milan · ITUniversity of Padua · ITBiomedical Research Networking Center on Neurodegenerative Diseases · ESFondazione IRCCS Istituto Neurologico Carlo Besta · ITInstitute of Neurological Sciences · ITMayo Clinic in Arizona · USNational Hospital for Neurology and Neurosurgery · GBOregon Health & Science University · USOspedale Garibaldi · ITOspedale Policlinico San Martino · ITPoliclinico San Matteo Fondazione · ITPresidio Ospedaliero · ITSalford Royal Hospital · GBSapienza University of Rome · ITUniversitat Autònoma de Barcelona · ESUniversity of Canterbury · NZUniversity of Catania · ITUniversity of Patras · GRUniversity of Turin · IT

Funding

IRCCS MONDINO FOUNDATION RC
6 · The paper itself

Abstract

backgroundParkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor and non-motor dysfunction. Dysphagia is a common symptom in PD, though it is still too frequently underdiagnosed. Consensus is lacking on screening, diagnosis, and prognosis of dysphagia in PD.

objectiveTo systematically review the literature and to define consensus statements on the screening and the diagnosis of dysphagia in PD, as well as on the impact of dysphagia on the prognosis and quality of life (QoL) of PD patients.

methodsA multinational group of experts in the field of neurogenic dysphagia and/or PD conducted a systematic revision of the literature published since January 1990 to February 2021 and reported the results according to PRISMA guidelines. The output of the research was then analyzed and discussed in a consensus conference convened in Pavia, Italy, where the consensus statements were drafted. The final version of statements was subsequently achieved by e-mail consensus.

resultsEighty-five papers were used to inform the Panel's statements even though most of them were of Class IV quality. The statements tackled four main areas: (1) screening of dysphagia: timing and tools; (2) diagnosis of dysphagia: clinical and instrumental detection, severity assessment; (3) dysphagia and QoL: impact and assessment; (4) prognostic value of dysphagia; impact on the outcome and role of associated conditions.

conclusionsThe statements elaborated by the Consensus Panel provide a framework to guide the neurologist in the timely detection and accurate diagnosis of dysphagia in PD.

Indexed as

Deglutition DisordersParkinson DiseaseDeglutitionHumansItalyPrognosisQuality of LifeDeglutition disordersDysphagiaParkinson's diseaseSwallowing disorders

Identifiers

PMID34417870
PMCPMC8857094
OpenAlexW3194573904

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.