Evidence map›Paper›PMID 34417836›Full record

ReviewAnalytical and bioanalytical chemistry2022

Recombinant antibodies and their use for food immunoanalysis.

Riikka Peltomaa, Rodrigo Barderas, Elena Benito-Peña, María C Moreno-Bondi

Open access · bronzeAbstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Advances in Immunological Methods for the Detection ofSensors (Basel, Switzerland) · 2026
    Review
  7. Establishment of human-relevantFrontiers in toxicology · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Riikka PeltomaaDepartment of Life Sciences, University of Turku, 20014, Turku, Finland.ORCID https://orcid.org/0000-0001-7041-3722
Rodrigo BarderasChronic Disease Programme, UFIEC, Instituto de Salud Carlos III, 28220, Madrid, Spain.ORCID https://orcid.org/0000-0003-3539-7469
Elena Benito-PeñaDepartment of Analytical Chemistry, Universidad Complutense de Madrid, 28040, Madrid, Spain. elenabp@ucm.es.
María C Moreno-BondiDepartment of Analytical Chemistry, Universidad Complutense de Madrid, 28040, Madrid, Spain. mcmbondi@ucm.es.ORCID https://orcid.org/0000-0002-3612-0675
Universidad Complutense de Madrid · ESInstituto de Salud Carlos III · ESUniversity of Turku · FI

Funding

FEDER funds from the AES-ISCIII PI20CIII/00019Spanish Ministry of Economy and Competitiveness RTI2018-096410-B-C21
6 · The paper itself

Abstract

Antibodies are widely employed as biorecognition elements for the detection of a plethora of compounds including food and environmental contaminants, biomarkers, or illicit drugs. They are also applied in therapeutics for the treatment of several disorders. Recent recommendations from the EU on animal protection and the replacement of animal-derived antibodies by non-animal-derived ones have raised a great controversy in the scientific community. The application of recombinant antibodies is expected to achieve a high growth rate in the years to come thanks to their versatility and beneficial characteristics in comparison to monoclonal and polyclonal antibodies, such as stability in harsh conditions, small size, relatively low production costs, and batch-to-batch reproducibility. This review describes the characteristics, advantages, and disadvantages of recombinant antibodies including antigen-binding fragments (Fab), single-chain fragment variable (scFv), and single-domain antibodies (V

Indexed as

AntibodiesFood AnalysisRecombinant ProteinsAnimalsBiosensing TechniquesImmunoassayAntibodiesRecombinant ProteinsAntibody fragmentBiosensingFood analysisImmunoassayRecombinant antibody

Identifiers

PMID34417836
PMCPMC8380008
OpenAlexW3193414958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.