Evidence map›Paper›PMID 34417559›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2021

A non-invasive left ventricular pressure-strain loop study on myocardial work in primary aldosteronism.

Yi-Lin Chen, Ting-Yan Xu, Jian-Zhong Xu, Li-Min Zhu, Yan Li, Ji-Guang Wang

Abstract read
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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Left ventricular structure and function in relation to sodium dietary intake and renal handling in untreated Chinese patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Role of α1-blockers in the current management of hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022
    Review
  9. Review
  10. Do diurnal changes in blood pressure affect myocardial work indices?Journal of clinical hypertension (Greenwich, Conn.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yi-Lin ChenDepartment of Cardiovascular Medicine, National Research Center for Translational Medicine, Centre for Cardiovascular Evaluations, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Ting-Yan XuDepartment of Cardiovascular Medicine, National Research Center for Translational Medicine, Centre for Cardiovascular Evaluations, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. xtyswallow@sina.com.
Jian-Zhong XuDepartment of Cardiovascular Medicine, National Research Center for Translational Medicine, Centre for Cardiovascular Evaluations, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Li-Min ZhuDepartment of Cardiovascular Medicine, National Research Center for Translational Medicine, Centre for Cardiovascular Evaluations, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yan LiDepartment of Cardiovascular Medicine, National Research Center for Translational Medicine, Centre for Cardiovascular Evaluations, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Ji-Guang WangDepartment of Cardiovascular Medicine, National Research Center for Translational Medicine, Centre for Cardiovascular Evaluations, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Ruijin Hospital · CNShanghai Institute of Hypertension · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the myocardial work derived from left ventricular pressure-strain loop in patients with primary aldosteronism or primary hypertension. We enrolled 50 patients with primary aldosteronism, 50 age- and sex-matched patients with primary hypertension, and 25 normotensive control subjects. We performed transthoracic echocardiography and speckle-tracking echocardiography-based left ventricular pressure-strain loop analysis to evaluate cardiac structure and function. Patients with primary aldosteronism and those with primary hypertension had similar clinic and ambulatory blood pressures, except that the former had a significantly (P = 0.03) higher nighttime systolic blood pressure. All subjects had normal left ventricular ejection fraction (66.4 ± 4.7%). Patients with primary aldosteronism had a greater left ventricular mass index than those with primary hypertension and the normal controls (111.0 ± 21.6 g/m

Indexed as

HyperaldosteronismHypertensionEchocardiographyHumansStroke VolumeVentricular Function, LeftVentricular PressureLeft ventricular pressure-strain loopMyocardial workPrimary aldosteronismPrimary hypertensionSpeckle tracking echocardiography

Identifiers

PMID34417559
OpenAlexW3194334457

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.