Evidence map›Paper›PMID 34417500›Full record

ArticleScientific reports2021

Target identification of hepatic fibrosis using Pien Tze Huang based on mRNA and lncRNA.

Jinhang Zhu, Di Zhang, Ting Wang, Zhiliang Chen, Luan Chen, Hao Wu, Cong Huai, Jing Sun, Na Zhang, Muyun Wei and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jinhang Zhu *Department of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Di Zhang *Department of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Ting WangBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Zhiliang ChenFujian Provincial Key Laboratory of PTH Natural Medicine Research and Development, Zhangzhou PTH Pharmaceutical CO., LTD, Zhangzhou, China.
Luan ChenBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Hao WuBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Cong HuaiBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Jing SunBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Na ZhangBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Muyun WeiBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Fei HongFujian Provincial Key Laboratory of PTH Natural Medicine Research and Development, Zhangzhou PTH Pharmaceutical CO., LTD, Zhangzhou, China. pzhhf123@126.com.
Shengying QinDepartment of Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China. chinsir@sjtu.edu.cn.
Shanghai Jiao Tong University · CNAnhui Medical University · CN

Funding

Sex differences in stress-alcohol interactions modulating amygdala activityR00AA021802 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI LOGRIP, MARIAN LEE · 2015 to 2017
$747k
Sex differences in stress-alcohol interactions modulating amygdala activityK99AA021802 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI LOGRIP, MARIAN LEE · 2013 to 2014
$279k
NIAAA NIH HHS K99 AA021802NIAAA NIH HHS R00 AA021802
6 · The paper itself

Abstract

Hepatic fibrosis is a spontaneous wound-healing response triggered by chronic liver injury. Pien Tze Huang (PZH), a traditional Chinese herbal medicine, has been widely used to treat various hepatic diseases in Asia. We used a CCl

Indexed as

AnimalsCluster AnalysisDrugs, Chinese HerbalGene Regulatory NetworksImmune SystemLiverLiver CirrhosisLiver Function TestsMaleMiceMice, Inbred C57BLOpen Reading FramesRNA, Long NoncodingRNA, MessengerStaining and LabelingDrugs, Chinese Herbalpien tze huangRNA, Long NoncodingRNA, Messenger

Identifiers

PMID34417500
PMCPMC8379174
OpenAlexW3194044019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.