Evidence map›Paper›PMID 34417441›Full record

ArticleTranslational psychiatry2021

Emotional adaptation during a crisis: decline in anxiety and depression after the initial weeks of COVID-19 in the United States.

Anastasia Shuster, Madeline O'Brien, Yi Luo, Laura A Berner, Ofer Perl, Matthew Heflin, Kaustubh Kulkarni, Dongil Chung, Soojung Na, Vincenzo G Fiore and 1 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  10. Assessment of PBC Pruritus From the ITCH-E Study: Quality of Life, Productivity, and Treatment Experiences.Liver international : official journal of the International Association for the Study of the Liver · 2025
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  20. COVID-19-Related Stressors and Clinical Mental Health Symptoms in a Northeast US Sample.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Anastasia Shuster *Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Madeline O'Brien *Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-1768-2442
Yi LuoFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA.ORCID 0000-0002-6169-8938
Laura A BernerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-1430-8028
Ofer PerlDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Matthew HeflinDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-0379-3582
Kaustubh KulkarniNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Dongil ChungDepartment of Biomedical Engineering, UNIST, Ulsan, South Korea.ORCID 0000-0003-1999-0326
Soojung NaNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Vincenzo G FioreDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Xiaosi GuDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA. xiaosi.gu@mssm.edu.ORCID 0000-0002-9373-987X
Icahn School of Medicine at Mount Sinai · USBiomedical Research Institute · USUlsan National Institute of Science and Technology · KR

Funding

Computational and electrochemical substrates of social decision-making in humansR01MH124115 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GU, XIAOSI, KISHIDA, KENNETH TUCKER · 2020 to 2024
$5.1M
Neurocomputational mechanisms of proactive social behavior deficits in autism spectrum disorderR01MH122611 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FOSS-FEIG, JENNIFER, GU, XIAOSI · 2020 to 2024
$3.9M
Neural, computational and behavioral characterization of dynamic social behavior in borderline and avoidant personality disorderR01MH123069 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI, KOENIGSBERG, HAROLD W · 2021 to 2025
$3.1M
The Influences of Eating and Fasting on Inhibitory Control in Bulimia Nervosa: A Computational Neuroimaging StudyK23MH118418 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BERNER, LAURA A. · 2019 to 2023
$963k
Brain Aromatase and Inhibitory Control in Bulimia NervosaR21MH124352 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HILDEBRANDT, THOMAS B · 2020 to 2020
$468k
Delineating proactive social behaviors in dynamic and multidimensional social spaceR21MH120789 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI, SCHILLER, DANIELA · 2019 to 2020
$466k
Icahn School of Medicine at Mount Sinai (ISMMS) N/ANIMH NIH HHS K23 MH118418NIMH NIH HHS R01 MH122611NIMH NIH HHS R01 MH123069NIMH NIH HHS R01 MH124115NIMH NIH HHS R21 MH120789NIMH NIH HHS R21 MH124352U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R01MH122611U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R01MH124115U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R21MH120789U.S. Department of Health & Human Services | NIH | National Institute on Minority Health and Health Disparities (NIMHD) R01MH123069
6 · The paper itself

Abstract

Crises such as the COVID-19 pandemic are known to exacerbate depression and anxiety, though their temporal trajectories remain under-investigated. The present study aims to investigate fluctuations in depression and anxiety using the COVID-19 pandemic as a model crisis. A total of 1512 adults living in the United States enrolled in this online study beginning April 2, 2020 and were assessed weekly for 10 weeks (until June 4, 2020). We measured depression and anxiety using the Zung Self-Rating Depression scale and State-Trait Anxiety Inventory (state subscale), respectively, along with demographic and COVID-related surveys. Linear mixed-effects models were used to examine factors contributing to longitudinal changes in depression and anxiety. We found that depression and anxiety levels were high in early April, but declined over time. Being female, younger age, lower-income, and previous psychiatric diagnosis correlated with higher overall levels of anxiety and depression; being married additionally correlated with lower overall levels of depression, but not anxiety. Importantly, worsening of COVID-related economic impact and increase in projected pandemic duration exacerbated both depression and anxiety over time. Finally, increasing levels of informedness correlated with decreasing levels of depression, while increased COVID-19 severity (i.e., 7-day change in cases) and social media use were positively associated with anxiety over time. These findings not only provide evidence for overall emotional adaptation during the initial weeks of the pandemic, but also provide insight into overlapping, yet distinct, factors contributing to depression and anxiety throughout the first wave of the pandemic.

Indexed as

COVID-19DepressionAdultAnxietyEmotional AdjustmentFemaleHumansPandemicsSARS-CoV-2United States

Identifiers

PMID34417441
PMCPMC8377451
OpenAlexW3195430565

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.